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Clinical Trial Summary

Young patients with relapsed or refractory classic Hodgkin's lymphoma will be treated with PD-1 inhibitor combined with decitabine as second-line salvage treatment for four cycles. If PR or CR was obtained after salvage treatment, patients will receive GBM conditioning regimen followed by ASCT as consolidation therapy. High-risk R/R cHL patients will be treated with PD-1 inhibitor after ASCT for 1 year. The purpose of current study is to determine the clinical efficacy and safety of PD-1 inhibitor combined with decitabine followed by ASCT as second-line treatment in patients with relapsed or refractory classic Hodgkin's lymphoma.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05137886
Study type Interventional
Source Institute of Hematology & Blood Diseases Hospital
Contact Dehui Zou, Dr.
Phone 86-022-23909282
Email zoudehui@ihcams.ac.cn
Status Recruiting
Phase Phase 2
Start date January 2022
Completion date January 2025

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