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HIV and Ovarian Reserve — VIHRO  

HIV Clinical Trial

Official title:
Evaluation of the Potential Impact of HIV and Its Treatments on Ovarian Reserve: Prospective Study

Clinical Trial Summary

Recent evidence suggests a decline in fertility of persons living with HIV (PLWH) (delayed pregnancies, sponteanous abortions, especially when patients receive an antiretroviral therapy, early menopause, amenorrhea and anovulatory cycles) with a possible decrease in ovarian reserve. However, indications of fertility preservation by freezing oocytes are nevertheless not clearly identified.

The objective of this study is to evaluate the ovarian reserve before and after the implementation of antiretroviral treatment in PLWH for whom the diagnosis of HIV has just been made.

Clinical Trial Description

This is a monocentric prospective cohort study with minimal risk and constraints. Ovarian reserve is compared between two groups: 30 PLWH, at time of diagnosis and 6, 12 and 18 months after initiation of an antiretroviral therapy, and 30 HIV negative women attending medically assisted procreation consultation for male infertility, age, BMI and smoking habits matched. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03572270
Study type Interventional
Source University Hospital, Clermont-Ferrand
Contact Patrick LACARIN
Phone 0473751195
Email placarin@chu-clermontferrand.fr
Status Not yet recruiting
Phase N/A
Start date June 2018
Completion date November 2022
View Details
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