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Altering Mechanisms of Frailty in Persons Living With HIV Aged 50 to 65 — ALTER  

Hiv Clinical Trial

Official title:
Altering Mechanisms of Frailty in Persons Living With HIV Aged 50 to 65

Clinical Trial Summary

People living with HIV are living longer as their disease is controlled with antiretroviral medications. Yet they are experiencing frailty more often and more than ten years earlier than those without HIV. In elderly persons without HIV, frailty is associated with decreased muscle strength and chronic inflammation. Less is known about what is driving early frailty in HIV or effective prevention measures for aging adults with HIV. It may be that having HIV infection impairs energy production by mitochondria within the cells and contributes to the muscle weakness and inflammation accompanying frailty in people living with HIV . This study will examine the impact of six weeks of moderately paced walking on energy production in the cells, inflammation markers and frailty scores in people living with well-controlled HIV who are aged 50 to 65.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04321603
Study type Interventional
Source University of Maryland, Baltimore
Contact
Status Withdrawn
Phase N/A
Start date May 30, 2020
Completion date May 30, 2020
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