HIV Clinical Trial
Official title:
Game Changers: Pilot Intervention to Empower HIV Clients as Prevention Advocates in Uganda
Verified date | May 2020 |
Source | RAND |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This randomized controlled pilot study of the "Game Changers" program will:
1. Assess the feasibility and acceptability of implementing an HIV prevention advocacy
intervention with people living with HIV who are in HIV care, and who will be trained to
be advocates of HIV protective behaviors within their social networks.
2. Assess preliminary intervention effects on a) protective behavior of the HIV-positive
clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART
adherence); and b) diffusion of prevention messages across the network, as assessed by
the content and extent of communication with network members about protective behaviors
(condom use, partner concurrency/number of partners, HIV testing, engagement in HIV
care, circumcision), HIV disclosure, and HIV stigma.
3. Explore characteristics of HIV-positive clients who more effectively engage in
prevention advocacy (in terms of socio-demographics, network characteristics, and
network position and type of alters receiving advocacy).
Status | Completed |
Enrollment | 99 |
Est. completion date | July 31, 2019 |
Est. primary completion date | July 31, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria (People living with HIV): - 18+ years old - In HIV care for > 1 year - Having disclosed serostatus to at least one person Inclusion Criteria (Social network members): - 18+ years old - Referred by a patient participant because they are family members, friends, or other people in patients' social network - knows patient participant's serostatus Exclusion Criteria: - Individuals who meet the inclusion criteria above will be eligible to participate, and no other exclusion criteria apply. |
Country | Name | City | State |
---|---|---|---|
Uganda | Infectious Diseases Institute | Kampala |
Lead Sponsor | Collaborator |
---|---|
RAND | Infectious Diseases Institute, Uganda |
Uganda,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in Engagement HIV Prevention Advocacy | Self-reported communication with social network members about protective behaviors. This is a composite of 14 survey items rated on a scale of 1 (low level of communication) to 5 (high level of communication). | Past 3 months, measured at baseline and 5 and 8 months post-baseline | |
Secondary | Change in Sexual Risk Behavior Among Alters | Increased percentage of self-reported condom use with main partner in past 3 months | Measured at baseline and 5 and 8 months post-baseline | |
Secondary | Change in HIV Treatment Adherence | Increased antiretroviral treatment adherence (self-reported % doses taken in past month) | Measured at baseline and 5 and 8 months post-baseline | |
Secondary | Change in Internalized HIV Stigma | Decreased rates of internalized HIV-related stigma on Internalized AIDS Stigma Scale (range=1-5, higher values = high stigma) | Measured at baseline and 5 and 8 months post-baseline | |
Secondary | Number of Participants Who Have Reported Their HIV Status to Their Main Partner | Increased self-reported rates of HIV status disclosure: Participants were asked if they had disclosed their HIV-serostatus to their main partner or spouse (yes/no). | Measured at baseline and 5 and 8 months post-baseline |
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