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HIV clinical trials

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NCT ID: NCT02044484 Recruiting - HIV Clinical Trials

HIV Clinic-Based Intervention to Improve ART Adherence and Prevent HIV Transmission

APTcare
Start date: January 2014
Phase: N/A
Study type: Interventional

This research, co-sponsored by the Centers for Disease Control and Prevention and the National Institute of Mental health, is conducted at six HIV clinics in the U.S. The research examines the effect of a clinic-based multi-component intervention delivered to HIV patients when they attend clinic for primary care. The study tests the hypothesis that the intervention will improve the viral load status of patients and improve attendance for HIV primary care.

NCT ID: NCT02043418 Active, not recruiting - HIV Clinical Trials

Outcome at 5 Years of Early Treated HIV Infected Infants in the PEDIACAM Project

PEDIACAM
Start date: November 2007
Phase:
Study type: Observational

This study aims to assess the long-term outcomes of children infected with HIV, having participated in the ANRS 12140 PediacamI study, in terms of: clinical and immunovirological response to ARV therapy, long-term ARV tolerance, and the impact of family environment and lifestyle on adherence to ARV treatment.

NCT ID: NCT02043080 Completed - HIV Clinical Trials

Optimizing Clinical Outcomes in HIV-Infected Adults & Children

Start date: August 2012
Phase: N/A
Study type: Interventional

This is a study to evaluate Xpert MTB/RIF as the first-line TB diagnostic test in HIV-infected adults and pediatric patients as a means to obtain faster, more accurate TB diagnosis.

NCT ID: NCT02043041 Completed - HIV Clinical Trials

Evaluation of the Quality of Self-collected Blood Spot Specimens for Laboratory HIV Testing - An InvolveMENt Sub Study

Start date: January 2014
Phase: N/A
Study type: Observational

We will invite a convenience sample of up to 45 enrolled subjects to participate in an optional, self-administered blood specimen collection procedure to determine optimal procedures for collection.

NCT ID: NCT02043015 Completed - HIV Clinical Trials

Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the acceptability and uptake of a combination package of biomedical, behavioral and community-level HIV prevention interventions and services for men who have sex with men (MSM) in South Africa.

NCT ID: NCT02042248 Completed - HIV Clinical Trials

A Phase I Study to Evaluate the Immunologic Response and Virologic Impact of AGS-004

Start date: March 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to: - find out the intensity and duration of the immune response after multiple injections of the investigational study product AGS-004 made from one's own dendritic cells and one's own strain of HIV; - understand the changes in the body's HIV DNA , and HIV-1 RNA in peripheral and resting CD4+ cells prior to and following administration of AGS- 004. - find out if low levels of HIV virus that are not detectable by standard HIV RNA assays will decrease following the administration of AGS-004. - find out if it is safe to give individuals with HIV multiple injections of AGS-004 made from the person's own dendritic cells and their own strain of HIV. - find out if administration of AGS-004 decreases the amount of latent HIV infection in resting CD4 cells

NCT ID: NCT02041247 Active, not recruiting - HIV Clinical Trials

Assessment of VAC-3S Therapeutic Properties When Combined With Standard ART in the Course of HIV-1 Infection

Start date: January 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the protective effect of VAC-3S in controlled HIV patients receiving standard of care antiretroviral treatment.

NCT ID: NCT02039921 Completed - HIV Clinical Trials

Observational, Retrospective, Multicenter Study to Describe the Reasons for the Change of the Regimen of Antiretroviral Therapy in HIV Patients

SWITCHART
Start date: October 2013
Phase: N/A
Study type: Observational

The study aims to describe the changes of combination antiretroviral therapy and the causes that motivated them.

NCT ID: NCT02038582 Completed - HIV Clinical Trials

Strategies to Increase HIV Testing, Linkages to Care, and Male Circumcision in Africa

Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine efficient, scalable, evidence-based strategies to link HIV positive individuals to care and HIV negative individuals to prevention measures, such as voluntary male circumcision.

NCT ID: NCT02038335 Completed - HIV Clinical Trials

HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC

Zim CHIC
Start date: February 2014
Phase:
Study type: Observational

This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract of healthy women. Immune cells are important because they help prevent infections from starting and help fight infections that have started. Immune cells are also the type of cells that HIV (human immunodeficiency virus) infects so understanding more about them will help to better understand how to prevent the spread of HIV. Immune cells will be studied from the reproductive tract of women who want to start using one of the following contraceptives: Depo-Provera (DMPA), NET-EN, MPA/E2 (Cyclofem®), the levonorgestrel subdermal implant (Jadelle® ), the etonogestrel subdermal implant (Implanon® or Nexplanon® ) and the copper IUD.