HIV Infections Clinical Trial
Lately researchers and clinicians have emphasized the health related quality of life.
Several reasons account for this trend. First of all, the advanced medical practices have
contributed to the increased life expectancy. Secondly, the pattern of diseases has shifted
from high acuity to chronicity. Therefore, the effectiveness of health care could not be
solely evaluated by the rates of morbidity and mortality. The state of patients’ quality of
life has become the pivotal indicator of the effectiveness of health care interventions. On
the other hand, patients’ subjective perceptions of health care are crucial factors in
treatment processes. Therefore quality of life becomes reference in choosing health care
interventions to enhance the benefits of patients.
The scopes of quality of life research include the essence of quality of life, the
measurements of quality of life and the relationships between quality of life and its
related factors, etc. The local researchers have long put efforts in quality of life
research. The results of these studies have contributed to the understandings of different
patients’ quality of life. However, the majority of studies have focused on specific
diseases. This study propose to extend the scope of quality of life research to study
patients’ quality of life of two severe illnesses, i.e. HIV infections and schizophrenia.
These two illnesses represent two severe physical and psychiatric illnesses. Even their
etiology, mechanisms, disease process, signs and symptoms, and treatments are different.
However, the similarities of these two illnesses include both are severe illnesses without
cure, both are stigmatized by the society. Patients with these two illnesses suffer in their
personal lives, social relations and quality of life. Therefore the current study to further
investigate and compare and contrast the essence of patients’ quality of life and their
related factors.
The proposed study is a second year study of the two-year study - The quality of life of
patients with severe illnesses (NSC93-2314-B-002-294). The first year study focused on the
investigation of the quality of life of patients with HIV infections (NSC93-2314-B-002-294).
The aim of this proposed study is to compare and contrast the quality of life and its
related factors of patients with schizophrenia and HIV infections. The contributions of this
study include the in-depth understandings of quality of life of patients with HIV infections
and schizophrenia and the comparison of quality of life of different illnesses. The results
serve as the foundations in future development of intervention programs to enhance patients’
quality of life and cost-effectiveness analyses.
n/a
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