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Hernia clinical trials

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NCT ID: NCT01607801 Completed - Umbilical Hernia Clinical Trials

Effect of Reoperation for Recurrence After Open Umbilical Hernia Repair

UMBI-REC
Start date: January 2007
Phase: N/A
Study type: Observational

background Operation for small umbilical hernias is one of the most common surgical procedures, but the best surgical technique, including the choice of suture or mesh remains unknown. It is well known that using non-absorbable sutures in closure of the abdomen, diminishes the risk of incisional hernias and wound healing problems.It has also been found that the use of resorbable suture in fixation of the mesh in Lichtesteins procedure leads to greater risk of recurrence of the hernia. Furthermore, it has been stated in smaller studies, that the use of the mesh in open operation for a small umbilical hernia has lower risk of recurrence (approx. 1-3%) than sutured repair (10-12 %). However, the scientific literature is deficient, with few patients. The purpose of this study is to describe reoperation rate of recurrence after small umbilical hernias, depending on choice of sutures in both regular repair and in mesh repair. Hypothesis: sutured repair with non-absorbable suture has lower recurrence rates than with other types of sutures, whereas mesh repair has even lower recurrence rates in small umbilical hernia repairs.

NCT ID: NCT01606449 Completed - Clinical trials for Paraesophageal Hernia

Follow-up of Patients Operated Upon for Type II-IV Hiatal Hernia

Start date: January 1980
Phase: N/A
Study type: Observational

Surgical therapy for gastroesophageal reflux disease (GERD) and hiatal hernia (HH) can achieve outcomes that afford the patient lifelong satisfaction. The published results obtained with this surgery may not be considered to be definitive in relation to the length of follow-up or patients' life expectancy. The real recurrence rates and the results of surgery for GERD are difficult to assess due to the lack of serial time points during the follow-up. Further bias may have been introduced into the analysis by a lack of appropriate controls. The results of surgical therapy for type II-IV HH are even more controversial because of the high rate of anatomical relapse and the different methods of follow-up adopted in reported case series. Aim of this study is to clarify the value of surgical therapy for type II-IV HH. The investigators report on patients who were followed up after surgery at various time points over the course of 30 years.

NCT ID: NCT01597011 Completed - Chronic Pain Clinical Trials

Long-term Follow-up After Laparoscopic Inguinal Hernia Repair Using Tisseel for Mesh Fixation

Start date: July 2012
Phase: N/A
Study type: Observational

In hernia repair a mesh is used to close the defect in the abdominal wall. This mesh is either secured with tissue penetrating devices (ex. staples,tacks or sutures) or fibrin glue (Tisseel/Tissucol) or left unfixated. The investigators believe, and previous studies indicate, that the use of fibrin glue greatly reduces the amount of postoperative complications (ex. chronic pain, impaired ejaculation in men or recurrence of the hernia)when compared with the use of tacks or staples. The aim of this study is to compare the recurrence rates and amount of postoperative complications in patients who have had inguinal hernia repair with fibrin glue and in patients who have had inguinal hernia repair with tacks, staples or sutures.

NCT ID: NCT01596049 Terminated - Clinical trials for Primary Inguinal Hernia

The Efficacy of a Self-fixating Mesh in Unilateral Open Inguinal Hernia Repair

Start date: May 2012
Phase: N/A
Study type: Observational

This study's objective is to assess the efficacy of a Self-fixating mesh in the surgical repair of unilateral inguinal hernia, which is becoming the new standard of care in open surgical repair of inguinal hernia. The study design is interventional, enrolling 300 patients above 18 years of age, admitted for elective repair in the surgical department of Rambam Medical Health Care Campus, an academic medical center. The study will assess several outcomes including post-surgical pain, recurrence, quality of life and post surgical complications (e.g. wound infection, the formation of hematoma or seroma, etc).

NCT ID: NCT01595230 Active, not recruiting - Internal Hernias Clinical Trials

Internal Hernias After Gastric Bypass Can be Prevented Safely With Primary Closure of All Mesenteric Defects With Clips

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether closure of all mesenteric defects with clips at the time of Gastric bypass, can avoid the complication of late bowel obstruction- internal hernias

NCT ID: NCT01594450 Completed - Ventral Hernia Clinical Trials

Biological Meshes in Infected Fields: a Randomized Controlled Trial

SIMBIOSE
Start date: May 2012
Phase: Phase 3
Study type: Interventional

The SIMBIOSE trial is a large multicenter phase III prospective randomized controlled single blinded trial comparing the use of biological mesh versus traditional wound care without biological mesh in patients with an infected incisional ventral hernia. The primary endpoint is 6-month infectious and/or wound morbidity. Secondary endpoints are wound infection rate at 45 days, 3 months and 1 year, recurrent hernia rates at 1, 2 and 3 years, postoperative pain, quality of life, time to healing, need for wound reoperation, impact of the cross-linked mesh structure, and medico-economic evaluation. One hundred patients need to be included.

NCT ID: NCT01592942 Recruiting - Inguinal Hernia Clinical Trials

Mesh Fixation in Lichtenstein Hernioplasty

Start date: August 2012
Phase: N/A
Study type: Interventional

This is a prospective, randomized multi-centre study to find out most safe, feasible, painless and cost-effective mesh fixation method in inguinal hernia operation. Three mesh fixation techniques are compared to find out best technique in local anaesthesia Lichtenstein operation. Our hypothesis is that glue fixation is safe, simple and cheap method compared to conventional Lichtenstein technique.

NCT ID: NCT01590940 Recruiting - Clinical trials for Evaluate the Use of a New Mesh Type in Open Inguinal Hernia Repair

Use of Parietex Plug and Patch Hernia System in Open Inguinal Hernia Repair

Start date: April 2012
Phase: N/A
Study type: Observational

The use of synthetic mesh plugs for open inguinal hernia repair has seen dramatic variability in the number and composition of meshes currently on the world market. The use of biomaterials (PLLA, PGA) in hernia mesh is a relatively new and innovative method. These selected polymers have the ability to degrade while implanted, allowing for sufficient natural tissue healing and scarring. This usage presumably favors a decrease in foreignness, inflammatory reaction, recurrence, and incidence of chronic groin pain. Prior studies with similar plug meshes in the same indication have yielded favorable results which require this mesh to be investigated in its specific application. Primary Objective Evaluate the incidence of peri-operative and post-operative complications after the application of the Parietex plug and patch hernia system in open inguinal hernia repair. We will assess the efficacy of this mesh by examination and the application of a pain scale at the following intervals: 1 month, 3 months, and 1 year, respectively. Assessment is intended to evaluate: - Patient report of pain via their Pain score - Wound complication - Incidence of chronic groin pain - Recurrence rate - Other complications Secondary Objectives Record the description and assessment of the Parietex plug and patch hernia system: - surgical technique - description of dissection and mesh placement - method of fixation - operative times, anesthesia choice - length of hospital stay - mesh handling characteristics - return to daily activities - overall patient satisfaction

NCT ID: NCT01589796 Recruiting - Adult Clinical Trials

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Start date: April 2012
Phase: N/A
Study type: Interventional

Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better. The investigators hypothesize that doing TAP block closer to the middle of the abdomen would result in improved pain relief due to simultaneous block of ilioinguinal/iliohypogastric nerves.

NCT ID: NCT01589276 Completed - Ventral Hernia Clinical Trials

Risk Factors and Results of Emergency Ventral Hernia Repair

Start date: January 2007
Phase:
Study type: Observational

The aim of present study was to evaluate the clinical course after emergency ventral hernia repair in terms of 30-day-readmission, -reoperation and -mortality and to identify risk factors for emergency repair.