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Hernia clinical trials

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NCT ID: NCT02589171 Completed - Clinical trials for Surgical Port Site Hernia

The neoClose Abdominal Closure vs Carter-Thomason Trial

Start date: February 12, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the neoClose abdominal closure to the standard Carter-Thomason closure in a bariatric surgery gastric bypass population.

NCT ID: NCT02587403 Completed - Ventral Hernia Clinical Trials

A Comparison of Fortiva and Strattice Tissue Matrices in Complex, Ventral Hernia Repair

Start date: December 2, 2015
Phase: N/A
Study type: Interventional

The objective of this study is to compare the effectiveness of Fortiva Porcine Dermis versus Strattice Reconstructive Tissue Matrix for the underlay reinforcement of complex ventral hernia repair and assess post-operative complication rates, long term hernia recurrence rates.

NCT ID: NCT02584153 Withdrawn - Ventral Hernia Clinical Trials

A Study of Fibrin Sealant Plus Silver Microparticles to Prevent Incisional Hernias Following Abdominal Surgery

HiP_1
Start date: January 2019
Phase: Phase 1
Study type: Interventional

Incisional hernias are a frequent consequence of abdominal surgery. Current clinical efforts are primarily focused on improving repair materials and surgical techniques to correct these hernias instead of the optimal solution: prevention. A product called MYOSEAL is currently being developed to prevent hernia formation after abdominal surgery by using fibrin tissue sealant and silver particles to prophylactically enhance the early wound healing of myofascial incisions. The purpose of this phase 1 study is to examine the safety of applying MYOSEAL immediately after abdominal wall suture closure in patients undergoing abdominal surgery. The investigators expect that applying this product to sutured myofascial incisions will increase collagen formation in the wound and thus prevent the formation of incisional hernias.

NCT ID: NCT02576184 Completed - Clinical trials for Incisional Hernia After Diverting Stoma Closure

Mesh Reinforcement During Temporary Stoma Closure After Sphincter-Saving Rectal Cancer Surgery

MEMBO
Start date: December 2015
Phase: N/A
Study type: Interventional

This study aim to assess long-term results of an incisional hernia-prophylactic mesh placement during stoma reversal after total mesorectal excision (TME) for rectal cancer

NCT ID: NCT02572622 Completed - Clinical trials for Lumbar Disc Herniation

Comparison of Different Treatment Methods in Lumbal Disc Herniation Treatment

Start date: February 2014
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effectiveness of three different treatment methods which consists spinal decompression, deep friction massage and exercise. The patients were separated three groups Group one received non-surgical spinal decompression therapy, group two received non-surgical spinal decompression, lumbar stabilization exercises and manual therapy, group three received manual therapy and lumbar stabilization exercises. All groups completed 15 sessions of therapy. In each session, pain severity was assessed with numeric analog scale, straight leg raise test applied and the degree of the hip flexion where the patient reported pain were recorded, respectively. Static, dynamic muscle strength-endurance tests were applied before the treatment sessions started, after the treatment sessions ended, six weeks after and three months after the study. Oswestry Disability Scale (ODI), Back Performance Scale (BPS), Lanss Neuropathic pain Questionnaire, Fear-Avoidance-Beliefs Questionnaire (FABQ) and McGill Pain Questionnaire were applied before the treatment sessions started, after the treatment sessions ended and three months after the study. Gradient of disc height and thickness of the herniation were assessed segmentally with magnetic resonance imagination (MRI) before the study and three months after the study.

NCT ID: NCT02564757 Completed - Clinical trials for Recurrent Hernia of Anterior Abdominal Wall

Does Pregnancy Increase Risk of Ventral Hernia Recurrence?

Start date: September 2015
Phase: N/A
Study type: Observational

The investigators will examine if pregnancy increases risk of ventral hernia recurrence

NCT ID: NCT02561910 Completed - Clinical trials for Unilateral Inguinal Hernia With Gangrene and Obstruction

Effectivity of Laparoscopic Inguinal Hernia Repair (TAPP) in Daily Clinical Practice - Early and Long-term Results

Start date: January 2000
Phase: N/A
Study type: Observational

The effectiveness of laparoscopic inguinal hernia repair still remains unclear. During a one year period a total of 1208 inguinal hernias in 952 patients were consecutively operated using the laparoscopic technique by a total of 11 general surgeons in daily clinical routine. Laparoscopic hernia repair in the TAPP technique seems to have the potential to become the standard procedure in inguinal hernia repair in future.

NCT ID: NCT02559102 Completed - Clinical trials for Neurodevelopmental Disorder

Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants

DEGA
Start date: July 2015
Phase: Phase 3
Study type: Interventional

This is a prospective randomized controlled trial comparing dexmedetomidine sedation with caudal anaesthesia, and general sevoflurane anaesthesia with caudal anaesthesia for inguinal herniotomies in neonates and infants below 3 months of age. The investigators will compare the efficacy and adverse events associated with each of these techniques and neurodevelopmental outcomes of the infants in each group at 6 months and 2 years of age.

NCT ID: NCT02549820 Recruiting - Clinical trials for Congenital Diaphragmatic Hernia

Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia

CHOP_FETO
Start date: July 2015
Phase: N/A
Study type: Interventional

CDH is a birth defect characterized by the development, very early in gestation, of a hole in the diaphragm, the breathing muscle that separates the chest from the abdomen. As a result, the intestines and other organs in the abdomen can move into the chest and press on the developing lungs. This prevents the lungs from growing and developing normally. In severe cases, CDH can lead to serious disease and death at birth. For these babies, treatment before birth may allow the lungs to grow enough before birth so these children are capable of surviving and thriving.

NCT ID: NCT02542085 Active, not recruiting - Incisional Hernia Clinical Trials

Comparison of Hybrid and Laparoscopic Incisional Hernia Repair

Start date: November 2012
Phase: N/A
Study type: Interventional

Study is a prospective, multicenter, randomized trial evaluating two laparoscopic incisional hernia repair methods: basic laparoscopic mesh repair (lap.) and a hybrid repair (laparoscopic mesh and fascial suturation). Patients are recruited prospectively from 10 Finnish Hospitals (Oulu, Jorvi, Hyvinkää, Kotka, Seinäjoki, Valkeakoski, Lahti, Kuopio, Kokkola, Loimaa). Patients are randomized to operative groups (lap. vs hybrid). Follow-up visits are scheduled at 1- and 12-month after surgery. Patients are evaluated for their clinical status and an ultrasound scan is performed. QoL-questionnaire and pain score (VAS) are reported. The primary end-points: - clinically and/or radiologically detected seroma in 1 month control - clinically and/or radiologically detected recurrent hernia in 1 year control The secondary end-points: - peri-and postoperative outcomes/ complications, morbidity, mortality - duration of hospital stay - pain scale (VAS) - Quality of Life (SF/Rand36)