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Hernia clinical trials

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NCT ID: NCT02632097 Completed - Inguinal Hernia Clinical Trials

Histoacrylâ„¢ vs. Suture for Mesh Fixation in Lichtenstein Hernioplasty: A Randomized Prospective Double-Blinded Study

Histoacryl1
Start date: March 2013
Phase: N/A
Study type: Interventional

This is a prospective, randomized double-blinded study to find out if mesh fixation with n-butyl-2-cyanoacrylate (NBCA) are more painless than conventional mesh fixation with sutures in inguinal hernia operation (Lichtenstein procedure) in day-case surgery. Our hypothesis is that glue fixation is safe, simple and fast method compared to conventional Lichtenstein technique.

NCT ID: NCT02625077 Withdrawn - Clinical trials for Gastroesophageal Reflux

Valvuloplasty as Alternative to Toupet Fundoplication for GERD

VANTAGE
Start date: January 2016
Phase: N/A
Study type: Interventional

This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new intervention will be done in order to determine cost-effectiveness and costs per quality-adjusted life-year (QALY).

NCT ID: NCT02620566 Completed - Anesthesia Clinical Trials

Caudal Block vs Local Wound Infiltration for Hernia Repair in Children

CBvsLWI
Start date: September 2015
Phase: Phase 1/Phase 2
Study type: Interventional

To our knowledge there is still no study comparing the local wound infiltration by itself without ilio-inguinal and ilio-hypogastric nerve block and caudal anesthesia. The aim of this study was to evaluate anesthesia and recovery profile in pediatric patients after inguinal hernia repair with caudal block (CB) or local wound infiltration (LWI).

NCT ID: NCT02616718 Completed - Hernia, Ventral Clinical Trials

Incisional Hernia Progression Over Time

INPRO
Start date: September 2015
Phase: N/A
Study type: Interventional

This is a prospective multicenter study of patients diagnosed with a medium to giant incisional hernia (transverse defect >7 cm). Patients referred to the surgical outpatient clinic are invited to participate in the study. As a standard, all patients who are examined for incisional hernia undergo CT scan according to a hernia protocol, before planning of surgical repair (baseline scan). After this CT scan, patients are seen in the out-patient clinic once again and either treated conservatively without surgery, or scheduled for elective surgical repair of the hernia. If surgery is planned, the patients participating in the study undergo an additional CT scan in hernia protocol, within two weeks prior to surgery (follow-up scan). If a conservative non-surgical approach is chosen, patients can still participate in the study and will undergo an additional CT scan after 28-32 weeks.

NCT ID: NCT02616406 Completed - Hernia, Inguinal Clinical Trials

Objective Measure of Recovery After Outpatient Surgery

Start date: November 2015
Phase:
Study type: Observational

This is a study using wearable monitoring devices, patient activity and sleep patterns to monitor pre and post operative following outpatient inguinal hernia surgery to determine when these parameters return to baseline.

NCT ID: NCT02604732 Recruiting - Inguinal Hernia Clinical Trials

Pre-operative Withdrawal of Aspirin in Laparoscopic Inguinal Hernia Repair

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

This study aims to assess the need to stop Aspirin before elective laparoscopic inguinal hernia repair. It will consist of 2 arms: patients who continue to take Aspirin perioperatively and patients who stop Aspirin 5-7 days before the surgery.

NCT ID: NCT02602093 Recruiting - Clinical trials for Lumbar Disk Herniation

Percutaneous Transforaminal Endoscopic Discectomy vs. Open Microdiscectomy for Lumbar Disc Herniation (PTED-study)

Start date: January 2016
Phase: N/A
Study type: Interventional

Rationale: Lumbosacral radicular syndrome (LSRS) is caused by a herniated lumbar nucleus pulposus (HNP) and the estimated annual incidence in The Netherlands ranges between 60,000 to 75,000 people. Open microdiscectomy is the standard surgical technique. In recent years, several surgical techniques have been developed including, percutaneous transforaminal endoscopic discectomy (PTED). While PTED is gaining popularity in The Netherlands, evidence of its effects is lacking, leading to a heated debate. The current position of Zorginstituut Nederland (ZiN) is that there is insufficient evidence to support its use; therefore, PTED is not financially covered. The consequence is, patients are forced to pay the costs of treatment themselves. This study is expected to provide the necessary data to answer the question regarding effects and costs of PTED vs. open microdiscectomy, and help resolve the current debate.

NCT ID: NCT02599623 Recruiting - Anesthesia Clinical Trials

Safety and Efficacy of Local Anesthesia in Emergency Inguinal Hernia Surgery

Start date: January 2016
Phase: N/A
Study type: Interventional

This prospective randomized is designed to evaluate the safety and efficacy of hernia repairs using local anesthesia compared with those using general anesthesia for patients with incarcerated hernia.

NCT ID: NCT02596802 Recruiting - Clinical trials for Congenital Diaphragmatic Hernia

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia

FETO
Start date: December 1, 2015
Phase: N/A
Study type: Interventional

The goal is to assess the feasibility and safety of implementing Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in fetuses with severe left Congenital Diaphragmatic Hernia (CDH) at UTHealth. UTHealth's success in this study (with an initial 5 patients) will determine the feasibility of UTHealth's future participation in multi-center trials of this intervention.

NCT ID: NCT02594241 Completed - Hernia, Ventral Clinical Trials

PreOperative Steroid in Abdominal Wall Reconstruction: A Double-blinded Randomized Clinical Trial

POSAR
Start date: March 2016
Phase: N/A
Study type: Interventional

Patients who undergo abdominal wall reconstruction for giant ventral hernia repair will be randomized to either methylprednisolone or saline preoperatively, to examine the effects of methylprednisolone on postoperative pain, nausea and recovery after giant ventral hernia repair.