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Hernia clinical trials

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NCT ID: NCT01170780 Completed - Inguinal Hernia Clinical Trials

Dexamethasone Versus Placebo in Optimizing the Postoperative Period After Laparoscopic Inguinal Hernia Repair

Start date: August 2010
Phase: Phase 3
Study type: Interventional

Does corticosteroid (dexamethasone) have an effect on the postoperative period after laparoscopic hernia repair, when it comes to pain, postoperative nausea and vomiting and convalescence. This randomized, double-blinded study compares dexamethasone versus placebo. The patients are recommended one day of convalescence. The medicine or placebo is given before operation. The patients fill out questionnaire before operation and three hours after operation and in the following three days. The patients also register when they return to normal activities and work.

NCT ID: NCT01162564 Completed - Ventral Hernia Clinical Trials

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

Start date: June 2010
Phase: N/A
Study type: Observational

This is a multi-center, observational study of incisional/ventral hernia repair with NG-TSM laparoscopically. The study is not randomized and has a single treatment design assessing NG-TSM intra-operatively, its ease of use and handling characteristics.

NCT ID: NCT01141335 Completed - Pain Clinical Trials

Polypropylene Mesh Versus Polytetrafluoroethylene (PTFE) Mesh in Inguinal Hernia Repair

Start date: September 2009
Phase: Phase 4
Study type: Interventional

To evaluate the safety and efficacy of the Lichtenstein's hernioplasty using Infinit® PTFE Mesh, and to compare it with the traditional Lichtenstein procedure performed with polypropylene mesh.

NCT ID: NCT01136603 Recruiting - Hernia Clinical Trials

TIGR vs Polypropylene (Permanent) Mesh: Randomised Trial

Start date: July 2010
Phase: Phase 2
Study type: Interventional

Hypothesis: TIGR mesh as a reconstruction material is a more effective mesh for the repair of the abdominal wall post lipectomy, transverse rectus abdominis myocutaneous (TRAM) / deep inferior epigastric perforator (DIEP) flap.

NCT ID: NCT01132209 Completed - Pain Clinical Trials

Suture Techniques to Reduce the Incidence of The inCisional Hernia

STITCH
Start date: October 2009
Phase: N/A
Study type: Interventional

The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia. In this multi center double-blinded prospective randomized controlled trial, in which a new suture technique using small bites is compared with the traditionally applied large bites (mass closure) technique for midline incisions.

NCT ID: NCT01117337 Completed - Inguinal Hernia Clinical Trials

Comparing Non-fixation of Mesh to Mesh Fixation in Laparoscopic Inguinal Hernia Repair

Start date: September 2008
Phase: Phase 4
Study type: Interventional

The purpose of the study is 1. To compare the recurrence rate of the laparoscopic total extra peritoneal inguinal hernia repair without fixation of the mesh to mesh fixation under spinal anesthesia 2. To test whether non-fixation of mesh leads to less pain compared to the repair when the mesh is fixed.

NCT ID: NCT01115400 Completed - Hernia Clinical Trials

Quality of Life Evaluations in Patients With Abdominal Wall Hernias

QOL
Start date: July 2007
Phase:
Study type: Observational

The aim of this study is to evaluate the quality of life in patients with abdominal wall hernias using a user-friendly survey that is designed specifically for this population of patients. The investigators would like to use this survey to elucidate how quality of life of the patient is changed with the presence of an abdominal wall hernia.

NCT ID: NCT01109771 Completed - Ventral Hernia Clinical Trials

Absorbable Versus Permanent Mesh Fixation Trial in Laparoscopic Midline Ventral Hernia Repair

SORBET
Start date: April 2010
Phase: Phase 4
Study type: Interventional

To compare the use of absorbable tackers versus permanent tack fixation using a polyester large pore mesh in laparoscopic midline ventral hernia repair in a multicenter (Belgian) prospective randomized single-blinded trial. All patients referred for elective midline ventral hernia repair should be assessed for eligibility and entered in a study log, detailing all included patients during the study period.

NCT ID: NCT01105039 Completed - Inguinal Hernia Clinical Trials

Detailed Pain Pattern After Laparoscopic Inguinal Hernia Repair

Start date: November 2009
Phase: N/A
Study type: Observational

Pain after laparoscopic groin hernia repair consist of different pain components (overall pain, shoulder pain, incisional pain and visceral pain). Thus it is important to find out which of these pain components that is most severe, so intervention can be targeted.

NCT ID: NCT01099033 Completed - Hiatal Hernia Clinical Trials

The Biologic Basis of Hernia Formation

Start date: August 2007
Phase:
Study type: Observational

The study will examine potential biological and genetic mechanisms leading to hiatal and paraesophageal hernia formation in predisposed individuals. It is expected that these patients will have defects in the normal production and maturation of collagen and other connective tissue proteins, thus leading to weakness in the diaphragm that may allow for spontaneous herniation. Comparison of tissue and blood samples from these patients (study group) will be made to those from individuals undergoing lower esophageal surgery who have not developed a concurrent hernia (i.e. esophageal myotomy for achalasia and laparoscopic gastric bypass or laparoscopic adjustable gastric banding for morbid obesity - control group).