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Hernia, Ventral clinical trials

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NCT ID: NCT06251583 Recruiting - Wound Infection Clinical Trials

Prevention of Incisional Hernia With Mesh-suture at Umbilical Trocar Site.

INDURATE
Start date: March 22, 2023
Phase: Phase 3
Study type: Interventional

Incisional hernia related to the umbilical trocar site is probably the most frequent complication after laparoscopic surgical procedures. However, this is an underestimated sequelae of laparoscopic surgery which may involve an important morbidity and an increase in healthcare costs. The incidence of incisional trocar site hernia ranges from 20 to 35% of patients after laparoscopic surgery depending on the different investigations. Prophylactic meshes have been tried in an attempt to reduce the incidence of this complication in obese patients. In that sense, suture-meshes can be an alternative to conventional meshes to improve the incidence of incisional hernias. INDURATE TRIAL aims to test if suture-mesh is capable of reducing the incidence of incisional hernia in patients with risk factors for the development of this frequent complication when compared with conventional monofilament sutures.

NCT ID: NCT06051578 Recruiting - Hernia, Ventral Clinical Trials

Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation

Start date: September 8, 2023
Phase:
Study type: Observational

The purpose of this study is to use a scale to learn more about the tension of the abdominal wall in hernia repairs without component separation. 1. What is the abdominal wall tension for hernias repaired without a component separation? 2. What patient factors contribute to greater abdominal wall tension? 3. Is there an association between abdominal wall tension before primary closure or bridging repair and patient outcomes? Participants will be asked to allow their surgeon to use a tension scale to measure the tension of the abdominal wall during surgery.

NCT ID: NCT06016426 Recruiting - Incisional Hernia Clinical Trials

Mass Closure vs Layer by Layer Closure

Start date: September 30, 2023
Phase: N/A
Study type: Interventional

to assess two different ways of closure of laparotomy in children and infants

NCT ID: NCT05985343 Recruiting - Ileus Clinical Trials

The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction

Start date: January 15, 2024
Phase: Phase 4
Study type: Interventional

The aim of the study is to determine if the usage of sugammadex would reduce the time to return of bowel function when compared to standard of care (neostigmine/glycopyrrolate) when used for neuromuscular blockade reversal in patients with open abdominal wall reconstruction (AWR).

NCT ID: NCT05925959 Recruiting - Clinical trials for Abdominal Wall Hernia

Preoperative Weight Loss for Open Abdominal Wall Reconstruction

Start date: June 19, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction. The main question is will abdominal wall specific quality of life (using the HerQLes survey) for the group undergoing upfront surgery be non-inferior compared to the group in the weight management program.

NCT ID: NCT05920200 Recruiting - Chronic Pain Clinical Trials

Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations

Start date: January 9, 2020
Phase:
Study type: Observational

The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia depending on surgical technique, mesh type and fixation suture material. For this purpose the investigators will analyze data from the Kalinigrad Hernia Registry (KHR).

NCT ID: NCT05906017 Recruiting - Abdominal Hernia Clinical Trials

Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach. 110 patients with midline abdominal wall defects will be randomized to either open or robotic-assisted surgery. The investigators will examine short and long-term complications through follow-up with clinical assessment as well as patient-reported outcome measures including pain, cosmetic appearance, and overall patient satisfaction. Furthermore, the investigators will study the difference in surgical stress response between the two methods measured from a variety of different biomarkers before and after the operation. A cost-effective analysis will be conducted for the robotic and open procedure.

NCT ID: NCT05734222 Recruiting - Incisional Hernia Clinical Trials

Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias

Start date: September 29, 2022
Phase: N/A
Study type: Interventional

The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by developing new surgical techniques. The main questions it aims to answer are: 1. To study the topographic and variant anatomy of vessels and nerves in the retromuscular, preperitoneal, postperitoneal and pre-abdominal cell spaces of the anterior abdominal wall. To determine the most probable sources of blood flow and lymph from the anatomical formations forming the bed of the endoprosthesis. 2. To develop technical, surgical techniques that allow to form an implant bed with minimal traumatization of blood vessels and nerves and reduce the risk of postoperative complications. 3. To develop a technique for plasty of the anterior abdominal wall in mid-lateral postoperative hernias with a combination of retromuscular and subaponeurotic spaces. The researchers will compare an experimental group in which a new method of preparing the implant place will be used and a control group in which standard methods of treating postoperative ventral hernias were used to see whether the new method affects the improvement of the postoperative period and the reduction of complications.

NCT ID: NCT05661097 Recruiting - Clinical trials for Abdominal Wall Hernia

Clinical Study of Hernia Ring Closure Method in Laparoscopic Abdominal Wall Hernia Repair

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

By comparing the time of closing the hernia ring, the degree of pain, and the recovery of gastrointestinal tract in different groups Intervening, infection, recurrence and medical cost, to find out whether patients with abdominal wall hernia have different hernias It is the best way to close the hernia ring under laparoscopy and provide evidence based medicine. with In the research process of the research group, a database on abdominal wall hernia will be established for the future Further study of hernia has laid a solid foundation.

NCT ID: NCT05620121 Recruiting - Incisional Hernia Clinical Trials

ACute Treatment of Incisional Ventral Hernia

ACTIVE
Start date: September 15, 2022
Phase:
Study type: Observational

This observational, retrospective study aims to examine surgical outcomes in non-elective surgery for incisional hernia. The main questions it aims to answer are: - 30-day morbidity - short- and long-term surgical outcomes Data will be retrospectively collected from participating centers and compared. Researchers will compare surgical outcomes of the minimally invasive and laparotomic approaches to see if there are relevant differences in surgical outcomes.