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Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer

Brain Metastases Clinical Trial

Official title:
Phase 1 Trial of Tucatinib, Trastuzumab, and Capecitabine With Stereotactic Radiosurgery (SRS) in Patients With Brain Metastases From HER-2 Positive Breast Cancer

Clinical Trial Summary

This research study will evaluate how well brain metastases associated with HER-2 positive breast cancer can be controlled using a type of radiation known as stereotactic radiosurgery (SRS) when combined with three therapeutic agents, tucatinib, capecitabine, and trastuzumab. The combined use of SRS with the three drugs is considered investigational.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05553522
Study type Interventional
Source Baptist Health South Florida
Contact Manmeet Ahluwalia, M.D., MBA
Phone (786) 596-2000
Email manmeeta@baptisthealth.net
Status Recruiting
Phase Phase 1
Start date September 18, 2023
Completion date November 1, 2025
View Details
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