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NCT03668158 Clinical Trial

Multi-center Study on Therapy-oriented Molecular Subtyping of Hepatocellular Carcinoma

Hepatocellular Carcinoma Clinical Trial

Official title:
Multi-center Study on Therapy-oriented Molecular Subtyping of Hepatocellular Carcinoma

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT03668158
Other study ID # ZJHZXU2017
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date November 20, 2018
Est. completion date July 1, 2020

Study information
Verified date October 2018
Source Zhejiang University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to establish molecular subtyping of HCC.

Description:

Hepatocellular carcinoma is one of the most common malignant tumors in the world with high incidence and mortality. Liver transplantation is the most effective treatment for HCC and is in high demand in China. However, recurrence of HCC among liver transplantation recipients is still a great challenge and threat to the survival of recipients. So it is of great significance to establish molecular subtyping of HCC and achieve precise selection of recipients. Based on large scales of samples, the investigator's study aims to establish multi-omics characteristic profiles of liver transplantation for HCC in integration of apparent biological characteristics, clinical management and prognostic information by utilizing genomics, transcriptomics and proteomics, etc. This study will contribute to the therapy-oriented molecular subtyping of HCC.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 500
Est. completion date July 1, 2020
Est. primary completion date May 1, 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

Liver transplantation due to HCC within Hangzhou criteria

Exclusion Criteria:

Liver transplantation due to HCC beyond Hangzhou criteria Liver transplantation due to other disease except HCC Multiple organ transplantation

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Zhejiang University

Outcome
Type Measure Description Time frame Safety issue
Primary recurrence rate 2 years
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