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Hemorrhage clinical trials

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NCT ID: NCT02684500 Completed - Clinical trials for Intracranial Aneurysm

Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study

Start date: April 11, 2016
Phase:
Study type: Observational

The purpose of this research study is to determine if the diameter and flow of the superior mesenteric artery in patients with aneurysmal subarachnoid hemorrhage undergoing hypertensive therapy for cerebral artery vasospasm are effected enough to justify withholding enteral nutrition.

NCT ID: NCT02675985 Completed - Clinical trials for Subarachnoid Hemorrhage

Early Intensive Physical Therapy in Subarachnoid Hemorrhage

Start date: August 2016
Phase: N/A
Study type: Interventional

This study will investigate the safety and feasibility of early intensive physical therapy for patients diagnosed with subarachnoid hemorrhage. Intervention will begin in the neurological Intensive Care Unit (ICU) and continue for 30 days or hospital discharge.

NCT ID: NCT02672891 Completed - Clinical trials for Postpartum Hemorrhage

Intrauterine Balloon Tamponade in the Management of Postpartum Hemorrhage

Start date: May 2011
Phase: N/A
Study type: Interventional

Intrauterine balloon tamponade in the management of postpartum hemorrhage in the obstetrics emergency ward in menoufiya university hospitals as a low resource setting.Guidelines for the management of postpartum hemorrhage involve a stepwise approach including the exclusion of retained products and genital tract trauma. Uterine atony, which is the most common cause, is dealt with uterine rubbing and various uterotonic agents. Among the new modalities introduced to arrest the bleeding is the uterine tamponade using various balloons and catheters. The condom catheter uses a sterile rubber catheter fitted with a condom for uterine tamponade .

NCT ID: NCT02670824 Completed - Clinical trials for Intracerebral Hemorrhage (ICH)

Safety Study of CN-105 Neuroprotective Peptide for Intracerebral Hemorrhage

Start date: December 2015
Phase: Phase 1
Study type: Interventional

This study evaluates the safety, tolerability, and pharmacokinetics (PK) of a single escalating dose and repeated doses of CN-105 in healthy adult participants. There will be about 48 subjects, 36 active and 12 placebo.

NCT ID: NCT02667600 Completed - Pregnancy Clinical Trials

Blood Loss Measurement During Cesarean Delivery

Start date: May 2016
Phase:
Study type: Observational

The aim of this study is to assess the ability of the Triton Device to measure blood loss among women undergoing elective and non-elective cesarean delivery. This patient population often experiences significant blood loss during surgery, and measurements of surgical blood loss are often inaccurate.

NCT ID: NCT02661672 Completed - Clinical trials for Intracranial Hemorrhage

INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage

Start date: October 14, 2016
Phase: N/A
Study type: Interventional

Objective: The primary objective of this multicenter prospective registry is to provide additional safety, technical outcomes and clinical outcomes data for minimally invasive endoscopic surgery (MIES) with Apollo or Artemis for the evacuation of supratentorial brain hemorrhage in adult patients who do not qualify for the concurrent INVEST Feasibility randomized controlled trial at active INVEST centers.

NCT ID: NCT02660567 Completed - Clinical trials for Postpartum Hemorrhage

Amr's Maneuver and Postpartum Hemorrhage

Start date: March 2016
Phase: N/A
Study type: Interventional

The impacts of using Amr's manoeuvre (cervical traction) on atonic postpartum hemorrhage is a randomized controlled, multi-centre study that aims to compare the incidence of post partum hemorrhage (PPH> 500 ml blood loss) within the first 24 hours of labor after using Amr's maneuver with active management of the third stage versus active management alone

NCT ID: NCT02659878 Completed - Clinical trials for Subarachnoid Hemorrhage

Takotsubo Cardiomyopathy in Patients Suffering From Acute Non-traumatic Subarachnoid Hemorrhage

Start date: February 2015
Phase:
Study type: Observational

Pupose: Takotsubo cardiomyopathy is a rare and not well-known complication of the subarachnoid hemorrhage. This form of heart failure, called as "broke heart" or "apical ballooning syndrome", was first described by Japanese authors at the beginning of 1990's. 1.5-2.2% of acute coronary syndrome is Takotsubo cardiomyopathy. Its predisposing factors, hypothetical parthenogenesis, diagnostic criteria and therapeutic methods are already known from the literature. The study intends to include all patients over 18 years of age who were admitted to our clinic within 48 hours after the bleeding regardless of gender, neurological status or age. Data to be registered within 24 hours after admittance: Instruments: - Intracranial blood flow characteristics:TCCD - using Transcranial Color Doppler; systolic, diastolic and mean blood flow velocity, Systolic / Diastolic ratio, pulsatility index - ECG abnormalities: Corrected QT Interval (QTc), T wave, ST segment, arrhythmia - Echocardiography (Ejection fraction%, exact location and degree of cardiac wall motion abnormalities) - documented with video recording Hypothesis: The risk of Takotsubo cardiomyopathy (TS) is increased if SAH is associated with more severe state, a greater degree of bleeding, intraventricular and/ or intracerebral hemorrhage. The definitive care of patients is postponed due to the appearance of TS, which could affect the final outcome.

NCT ID: NCT02655653 Completed - Bleeding Clinical Trials

Efficacy of Tranexamic Acid and Epsilon-aminocaproic Acid in Reducing Bleeding and Transfusions in Cardiac Surgery

Start date: October 2008
Phase: Phase 3
Study type: Interventional

The investigators primary objective is to compare the effectiveness of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) in reducing bleeding and transfusion in cardiac surgery, with the hypothesis that TA is more effective. The investigators also seek to further examine the clinical benefits and adverse effects profiles of epsilon-aminocaproic acid and tranexamic acid.

NCT ID: NCT02654054 Completed - Uterine Fibroids Clinical Trials

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Start date: December 22, 2015
Phase: Phase 3
Study type: Interventional

This study seeks to evaluate the efficacy, safety and tolerability of elagolix alone and in combination with estradiol/norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.