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Hemorrhage clinical trials

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NCT ID: NCT02957292 Completed - Contraception Clinical Trials

A Study to Compare the Menstrual Bleeding Profile Among Jaydess® and Copper Intrauterine Device (IUD) Users. COLIBRI STUDY (Copper and Levonorgestrel IUD Barcelona Research Initiative).

COLIBRI
Start date: June 1, 2016
Phase: Phase 4
Study type: Interventional

The intrauterine device (IUD) is a long-term birth control method that has demonstrated high contraceptive efficacy and effectiveness due to its high compliance, adherence and persistence of use. The IUD has a global prevalence rate around 14% in women of reproductive age. Side effects are the main reason for IUD use discontinuation. The most common reasons for copper IUD discontinuation are increased menstrual bleeding, irregular bleeding and dysmenorrhea, whereas in the case of 52mg Levonorgestrel IUD are irregular bleeding and amenorrhea. In 2014, a new hormonal IUD containing13,5mg of Levonorgestrel was marketed in Spain. There are many studies comparing the two Levonorgestrel IUDs. However, there is any study comparing the IUD 13,5mg Levonorgestrel with classic copper IUDs. The hypothesis of this trial is that Levonorgestrel (13,5mg) IUD users have a menstrual bleeding pattern with fewer days than Copper 380 mm2 IUD users. This is a Phase IV, national single-center, randomized 1: 1, single-blind, comparative, parallel controled trial.

NCT ID: NCT02954068 Completed - Clinical trials for Postpartum Hemorrhage

IV Versus IM Administration of Oxytocin for Postpartum Bleeding

Start date: December 1, 2016
Phase: Phase 4
Study type: Interventional

This double-blind, randomized controlled trial will evaluate the effect of the route of administration of 10 IU of oxytocin on the average blood loss postpartum. Participants will be randomized to receive 10 IU of oxytocin by IV infusion or 10 IU of oxytocin by injection IM

NCT ID: NCT02946931 Completed - Hemorrhage Clinical Trials

All-Case Surveillance of Prizbind®

Start date: November 18, 2016
Phase:
Study type: Observational

To evaluate safety and effectiveness of Prizbind® for Intravenous Solution 2.5 g under Japanese clinical condition.

NCT ID: NCT02944851 Completed - Clinical trials for Blood Donors, Traumatic Blood Loss

Comparison of the Accuracy of Non-invasive Hemoglobin Measurement (SpHb) and Vena Cava Inferior Ultrasound

Start date: March 2016
Phase:
Study type: Observational

The aim of this work is determine the more successful noninvasive method by comparison of two noninvasive methods ( IVC ultrasound - noninvasive hemoglobin measurement (SpHb)) that used in the detection of patients with blood loss. The works were completed in 6 months. The study was conducted at the blood donation center and in Emergency department. Vital parameters were measured and recorded before making the voluntary blood donation. Following Masimo brand portable device fingers SpHb value was measured.Then IVC diameter of patients in the supine position were measured using ultrasonography. Then he left to donors return in routine blood donation programme. A unit (500ml) of blood were drawn from each donor. After the blood donation process measured and recorded the vital signs again. SpHb was measured noninvasively from finger again. Following these measurements were recorded again by measuring the diameter of IVC.

NCT ID: NCT02943655 Completed - Clinical trials for Heavy Menstrual Bleeding

Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause

Start date: November 1, 2017
Phase: Phase 3
Study type: Interventional

Abnormal uterine bleeding encompasses abnormalities in the regularity, duration of flow, frequency, and/or blood flow volume relative to normal menstruation. Of these menstrual abnormalities, heavy menstrual bleeding (HMB), defined objectively as a blood loss of 80 ml or more per menstrual cycle , which is unrelated to pregnancy or known pelvic or systemic disease.

NCT ID: NCT02938585 Completed - Clinical trials for Congenital Bleeding Disorder

Efficacy and Safety of Turoctocog Alfa for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Chinese Patients With Haemophilia A

guardian TM 7
Start date: December 12, 2016
Phase: Phase 3
Study type: Interventional

This trial is conducted in China. The aim of this trial is to evaluate the clinical efficacy of turoctocog alfa in treatment of bleeding episodes in Chinese patients with severe haemophilia A (FVIII≤1%).

NCT ID: NCT02935985 Completed - Cerebral Hemorrhage Clinical Trials

Emergency Management of Spontaneous Intracerebral Haemorrhage - Biomarkers

EsICH
Start date: December 12, 2016
Phase:
Study type: Observational

The bio-markers substudy of EsICH is designed to recruit patients with acute (first 8h) spontaneous intracerebral hemorrhage and assess a series of biological parameters (CBC, glucose, cholesterol, LDL cholesterol, triglycerides) and point-of-care bio-markers (cTnI, hsCRP, D-Dimer) in order to predict the functional outcome of these patients and to determine their input for early risk stratification and prognosis.

NCT ID: NCT02935751 Completed - Hemorrhage Clinical Trials

Apixaban Discontinuation Prior to Major Surgery

ADIOS
Start date: October 2016
Phase:
Study type: Observational

The ADIOS study is a prospective, observational study will evaluate one hundred and thirty (130) patients with non-valvular atrial fibrillation who are currently receiving treatment with apixaban as indicated to reduce the risk of stroke or systemic embolism, and who require an elective major surgical or invasive procedure will be included in the study. The purpose of the study is to evaluate the efficacy of the recommended pre-procedure washout period of 48 hours.

NCT ID: NCT02934789 Completed - Clinical trials for Heavy Menstrual Bleeding

Effectiveness of Truclear on Patient Quality of Life

HSCMyomecty
Start date: September 2014
Phase: N/A
Study type: Interventional

This study aims to evaluate the quality of life in patients treated for submucosal leiomyomas using the Truclear hysteroscopic morcellator compared to women managed medically. Study population includes women age 18 and older with symptomatic submucosal myomas. Patients will be asked to complete the Uterine Myoma Symptom and Health-related Quality of Life Questionnaire (UFS-QOL) at enrollment and at 1, 3, and 6 months after treatment.

NCT ID: NCT02929563 Completed - Clinical trials for Gastrointestinal Hemorrhage

Pediatric Intensive Care Ulcer Prophylaxis Pilot Trial

PIC-UP
Start date: January 9, 2017
Phase: Phase 3
Study type: Interventional

This study tests the feasibility of a large study of stress ulcer prophylaxis in critically ill children. Children admitted to the Pediatric Intensive Care Unit who are expected to require mechanical ventilation for more than 48 hours will be randomized to intravenous pantoprazole 1 mg/kg or matching placebo once daily until they no longer need mechanical ventilation.