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Hemorrhage clinical trials

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NCT ID: NCT00515281 Active, not recruiting - Clinical trials for Bronchopulmonary Dysplasia

Inhaled Nitric Oxide and Neuroprotection in Premature Infants

NOVA2
Start date: May 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether inhaled nitric oxide improves the neurological outcome for premature infants.

NCT ID: NCT00507104 Completed - Clinical trials for Traumatic Brain Injury

Pituitary Functions After Traumatic Brain Injury (TBI) and/or Subarachnoid Hemorrhage (SAH)

Start date: September 2006
Phase:
Study type: Observational

This study performs assessments of pituitary functions by basal hormone levels in the acute phase after TBI and/or SAH followed by detailed endocrine tests (insulin-induced hypoglycemia or growth hormone releasing hormone-arginine-corticotropin releasing hormone-leuteinizing hormone releasing hormone [GHRH-arginine-CRH-LHRH] test) after 4 and 12 months.

NCT ID: NCT00506103 Completed - Hemorrhage Clinical Trials

The No-Tie Technique Using the Harmonic Scalpel in Total Thyroidectomy With Central Neck Dissection: A Prospective Randomized Study

Start date: October 2006
Phase: N/A
Study type: Observational

To investigate the safety and efficacy of the no-tie technique using the harmonic scalpel (HS) in terms of the operating time and complications in total thyroidectomy with central neck dissection (CND). Recently, the HS has been used as an alternative to conventional hand-tied ligation for hemostasis in thyroid surgery, which is a time-consuming procedure. Very limited data have been published on evidence of its safety in total thyroidectomy accompanied by CND without supplementary hand-tied ligation.

NCT ID: NCT00505505 Recruiting - Clinical trials for Traumatic Brain Injury

Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy

Start date: January 2002
Phase: Phase 4
Study type: Interventional

Strict glycemic control improves mortality and morbidity of patients admitted to the postoperative intensive care unit (ICU). The investigators would like to know if this therapy could improve the long term neurologic and cognitive outcomes of patients treated for acute subarachnoid hemorrhage with either a surgical or intravascular approach.

NCT ID: NCT00491192 Recruiting - Clinical trials for Traumatic Brain Injury

Normothermia in Patients With Acute Cerebral Damage

Start date: June 2007
Phase: Phase 4
Study type: Interventional

The purpose of our study is to verify wherever normothermia (achieved with diclofenac administration) may improve intracranial pressure control and may limit secondary cerebral damage thus positively influencing outcome in patients with acute cerebral damage admitted to ICU.

NCT ID: NCT00490464 Completed - Clinical trials for Subarachnoid Hemorrhage

Safety and Efficacy of Nicardipine for the Control of Blood Pressure After SAH

Start date: June 2004
Phase: N/A
Study type: Observational

The purpose of this research is to explore ways to improve and simplify control of blood pressure in patients with SAH or ICH. This research will be done by comparing tow different medications that are routinely used to help control blood pressure. None of the medications used in this study nor any procedures performed are experimental.

NCT ID: NCT00488462 Completed - Hemorrhage Clinical Trials

Non-Pneumatic Anti-Shock Garment for Obstetrical Hemorrhage: Zambia and Zimbabwe

NASG
Start date: October 2007
Phase: N/A
Study type: Interventional

This trial will address the question of whether early application of the Non-pneumatic Anti-Shock Garment (NASG) at the Satellite Health Facility (SHF) level before transport to a Referral Hospital (RH) will decrease maternal mortality and morbidity. The available evidence indicates that the NASG substantially decreases blood loss, but there is no evidence that its application will reduce extreme adverse outcomes. It is also not known if possible side effects associated with NASG use might outweigh potential benefits. This study would rigorously test the effectiveness of the NASG using an experimental design with adequate power to detect statistically significant decreases in morbidity and mortality.

NCT ID: NCT00487461 Terminated - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid Hemorrhage

Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether treatment with a drug called Simvastatin prevents and improves outcome in patients who have Subarachnoid bleeding. Simvastatin is currently approved for the treatment of high cholesterol levels.

NCT ID: NCT00479362 Completed - Thrombosis Clinical Trials

Anticoagulant Therapy During Pacemaker Implantation

FINPAC
Start date: September 2005
Phase: Phase 4
Study type: Interventional

There are no established guidelines regarding interruption of warfarin anticoagulant therapy prior to surgical implantation of cardiac pacemakers. Continuing the anticoagulant could potentially result in increased bleeding complications from the implantation surgery, whereas discontinuing the anticoagulant could predispose the patient to blood clots and strokes. In this study we intend to randomly assign warfarin-treated patients either into interrupted or continued warfarin therapy prior to pacemaker implantation with the purpose of establishing the rate of complication in these groups. Our hypothesis is that a cardiac pacing device can be safely implanted without discontinuation of the anticoagulant therapy.

NCT ID: NCT00475553 Completed - Clinical trials for Breakthrough Bleeding

Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®

Start date: May 2006
Phase: N/A
Study type: Interventional

The purpose of this research study is to evaluate the best way to manage breakthrough spotting and bleeding during an extended use regimen of NuvaRing®. Ease of use and acceptability of a flexible regimen of NuvaRing® will also be evaluated. A comparison of cyclic mood symptoms, pelvic pain, and headaches will be made between a standard 21/7 regimen and an extended regimen.