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Hemorrhage clinical trials

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NCT ID: NCT02995928 Recruiting - Clinical trials for Subarachnoid Hemorrhage, Aneurysmal

Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage

Start date: May 4, 2017
Phase: N/A
Study type: Interventional

Decompressive craniectomy has been reported for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH). But no prospective randomised controlled trials have yet been undertaken to confirm its effect.The purpose of the study is to determine whether decompressive craniectomy combine aneurysm clipping surgery or endovascular coiling will improve clinical outcomes of poor-grade aSAH patients.

NCT ID: NCT02991612 Completed - Cirrhosis Clinical Trials

Rifaximin in Patients With Gastroesophageal Variceal Bleeding

RFXM
Start date: November 25, 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the safety and efficacy of Rifaximin in the treatment of cirrhotic gastroesophageal variceal bleeding.

NCT ID: NCT02991157 Completed - Clinical trials for Subarachnoid Hemorrhage, Aneurysmal

Noninvasive Assessment of Cerebral Oxygenation and Cardiac Function in Patients With Neurovascular Diseases

Start date: December 2016
Phase:
Study type: Observational

This prospective observational study will assess the regional cerebral oxygen saturation and cardiac output non-invasively in patients with subarachnoid hemorrhage during nimodipine administration for the prevention/management of cerebral vasospasm.

NCT ID: NCT02989155 Completed - Blood Loss Clinical Trials

Tranexamic Acid Use and Blood Loss in Total Hip Arthroplasty

Start date: January 2016
Phase: N/A
Study type: Observational

The purpose of this study is to determine the need for a blood transfusion during surgery and to evaluate the levels of certain proteins in the blood when given tranexamic acid.

NCT ID: NCT02988154 Recruiting - Hydrocephalus Clinical Trials

Simulation Efficacy in Neurosurgical Education

SENSE
Start date: June 2016
Phase: N/A
Study type: Observational

This study aims to investigate the efficacy of simulation in neurosurgical training.

NCT ID: NCT02987218 Completed - Clinical trials for Postoperative Cognitive Function

Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery

Start date: July 2015
Phase: Phase 4
Study type: Interventional

Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by the rupture of an intracranial aneurysm and accumulation of blood in the subarachnoid space with 30 to 40% mortality rate. Amongst the survivors 40-50% suffers disability due to cognitive decline.Trends towards early surgery offers challenge to anesthesiologist to provide optimum brain relaxation and simultaneously maintaining stable hemodynamics. Anesthetic agents are administered to conduct smooth neurosurgical procedure. These agents may affect patient's cognitive function postoperatively.Currently most common anesthetic agents used are either intravenous hypnotic agents (propofol) or volatile inhalational agents (isoflurane/sevoflurane/desflurane). Provision of neuroprotection with propofol and volatile inhalational agents has been studied by various authors.Not many studies have been performed in patients undergoing aneurysmal clipping surgeries looking into effects of various anesthetic agents on intraoperative (I/O) brain condition, I/O hemodynamic and POCD.Thus present study is planned to compare propofol and desflurane for long term postoperative cognitive decline in patients undergoing surgery following aneurysmal subarachnoid hemorrhage.

NCT ID: NCT02983786 Completed - Clinical trials for Traumatic Brain Injury

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor

NNOM
Start date: December 2015
Phase:
Study type: Observational

The goals of the project are to evaluate a noninvasive monitor of brain metabolism and blood flow in critically ill humans. If validated, such a reliable noninvasive brain blood flow and metabolism monitor, by allowing physiologic and pharmacologic decisions based on real-time brain physiology, potentially will become an important tool for clinicians in their efforts to prevent additional brain tissue death in patients admitted with stroke, brain hemorrhage and traumatic brain injury.

NCT ID: NCT02983591 Completed - Clinical trials for Prevention of Post Partum Hemorrhage After Labor Induction

Effect of Misoprostol in Reducing Post Partum Hemorrhage After Labor Induction by Oxytocin

Start date: November 2016
Phase: N/A
Study type: Interventional

The use of Oxytocin for labor induction may cause receptor exhaustion and thus making its use in the third stage of labor ineffective in reducing post partum blood loss as compared to other uterotonics.So, we studied the effect of other uterotonic which is misoprostol in reducing post partum hemorrhage.

NCT ID: NCT02981758 Completed - Clinical trials for Post-partum Hemorrhage (PPH)

Accurate Display of Postpartum Hemorrhage Using Triton (ADOPT)

ADOPT
Start date: July 2016
Phase:
Study type: Observational

A comparison of reported estimated blood loss with quantified blood loss in all patients whose medical records indicate Triton was used during their vaginal delivery.

NCT ID: NCT02980497 Completed - Gingivitis Clinical Trials

Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study

Start date: September 2013
Phase: N/A
Study type: Interventional

The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and an alcohol essential oil containing mouthrinse. A negative control group using only an ADA Accepted anticavity toothpaste will be included.