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Hemorrhage clinical trials

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NCT ID: NCT00116350 Completed - Clinical trials for Postpartum Hemorrhage

Misoprostol for the Treatment of Postpartum Hemorrhage

Start date: July 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether misoprostol is as effective as oxytocin for treating primary postpartum hemorrhage (PPH) with uterine atony as the suspected cause in two circumstances: 1) where women have received prophylactic uterotonics in the third stage of labor; and 2) where no prophylactic uterotonics have been given in the third stage of labor.

NCT ID: NCT00114088 Completed - Menorrhagia Clinical Trials

Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)

Start date: November 1997
Phase: Phase 3
Study type: Interventional

STOP-DUB is a multicenter randomized clinical trial that is assessing the efficacy and effectiveness of hysterectomy versus endometrial ablation (EA) for dysfunctional uterine bleeding (DUB) in women for whom medical management has not provided relief.

NCT ID: NCT00113568 Completed - Menorrhagia Clinical Trials

Safety Study of XP12B in Women With Menorrhagia

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety of XP12B in women with heavy menstrual bleeding associated with menorrhagia.

NCT ID: NCT00111085 Completed - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH)

CONSCIOUS-1
Start date: January 10, 2005
Phase: Phase 2
Study type: Interventional

The purpose of the study is to measure how effective and safe three different doses of the drug clazosentan are in preventing vasospasm after subarachnoid hemorrhage.

NCT ID: NCT00108758 Completed - Clinical trials for Congenital Bleeding Disorder

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Start date: March 2004
Phase: Phase 2
Study type: Interventional

This trial is conducted in Africa, Asia, Europe, South America, and the United States of America (USA). The purpose of this study is to evaluate the effectiveness of secondary prophylactic treatment with NovoSeven® in haemophilia A and B patients with inhibitors.

NCT ID: NCT00107874 Completed - Clinical trials for Postpartum Hemorrhage

Oral Misoprostol Versus Intravenous Oxytocin in Preventing Blood Loss After Non-scheduled Cesarean Section

Start date: January 1999
Phase: Phase 2
Study type: Interventional

Postpartum hemorrhage (PPH) ranks among the leading causes of maternal morbidity and mortality, both in developed and developing countries. With this trial, we sought to determine the effectiveness of oral misoprostol as an uterotonic drug in comparison with intravenous oxytocin, in patients with a low risk of PPH undergoing non-scheduled Cesarean section. We therefore compared the intra- and postoperative blood loss, as well as drug related side effects in patients, treated by the same surgical and anesthesiological team in one institution.

NCT ID: NCT00104455 Completed - Healthy Clinical Trials

Dose Response to Recombinant Factor VIIa When Administered for Bleed

Start date: June 2004
Phase: Phase 1
Study type: Interventional

This trial is conducted in the United States of America (USA). The purpose of this trial is to investigate the dose response to recombinant factor VIIa in healthy volunteers when administered for bleed.

NCT ID: NCT00097123 Completed - Pregnancy Clinical Trials

RCT of Misoprostol for Postpartum Hemorrhage in India

Start date: September 2002
Phase: N/A
Study type: Interventional

Death rates for pregnant women in rural India are approximately forty-five times higher than in the United States. Bleeding after the birth of a child and underlying anemia are the primary causes of mothers' deaths and sickness in rural India. This study assesses the effectiveness of an oral drug, misoprostol, given in the late stage of labor to reduce the incidence of maternal bleeding following births assisted by midwives in selected sites in Belgaum District, Karnataka, India.

NCT ID: NCT00075959 Completed - Clinical trials for Intracerebral Hemorrhage

Safety of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke

Start date: August 2004
Phase: Phase 2
Study type: Interventional

This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system. The primary objective was to assess the safety and tolerability of NXY-059 compared to placebo.

NCT ID: NCT00071565 Completed - Clinical trials for Subarachnoid Hemorrhage

Familial Intracranial Aneurysm Study II

Start date: September 2002
Phase: N/A
Study type: Observational

The purposes of this study are to identify possible genes that may increase the risk of aneurysm development in the brain, and to determine the effect of environmental factors such as cigarette smoking and high blood pressure on the expression of these genes.