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Hemodialysis clinical trials

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NCT ID: NCT00906555 Completed - Hemodialysis Clinical Trials

The Effect of Different Dosages of Solute Clearance on Outcome in Twice Weekly Hemodialysis Patients

Start date: June 2009
Phase: Phase 4
Study type: Interventional

Adequacy of solute clearance makes a profound impact on clinical outcome in maintenance hemodialysis patients. Thus far, guidelines on the target of solute clearance (Kt/V or URR) are based on patients with three dialysis sessions per week. However, quite a few patients have their dialysis sessions twice per week in China. The dialysis target of solute clearance in this population remains to be elucidated. The aim of this study was to explore the optimum target solute clearance (Kt/V or URR) in maintenance hemodialysis patients with two dialysis sessions per week. Two groups of hemodialysis patients with different Kt/V (1.2 ≤ Kt/V < 1.7 versus Kt/V ≥ 1.7) will be followed until 96 weeks in this prospective, randomized, multi-center, interventional study.

NCT ID: NCT00893165 Completed - Hemodialysis Clinical Trials

Does Moderate Physical Activity in Hemodialysis Patients Reduce Inflammation?

Start date: January 2010
Phase: N/A
Study type: Observational

The purpose of this study is to observe a potential benefit of moderate physical activity by using bed mounted cycles during hemodialysis treatment sessions on inflammatory markers in the blood of patients with end-stage renal disease (ESRD).

NCT ID: NCT00891813 Completed - Hemodialysis Clinical Trials

Effectiveness and Safety of IV Zemplar in Patients on Hemodialysis and With Secondary Hyperparathyroidism Using iPTH/100 as Initial Dose

Start date: May 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to observe the effectiveness and safety of the use of a low initial dose regime (iPTH/100) in chronic kidney disease patients with secondary hyperparathyroidism (PTH>300pg/mL) and that require dialysis at least 3 times per week.

NCT ID: NCT00889564 Completed - Hemodialysis Clinical Trials

HeRO Vascular Access Device Bacteremia Study

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of the HeRO Vascular Access Device in access challenged (e.g., catheter-dependent) hemodialysis patients. It is hypothesized the bacteremia rate associated with the HeRO device will be lower than a historical literature control of tunneled dialysis catheters.

NCT ID: NCT00885300 Completed - Hemodialysis Clinical Trials

Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.

NCT ID: NCT00883831 Completed - Clinical trials for End Stage Renal Disease

The Effectiveness and the Safety of Acupuncture for Symptomatic Care of Hemodialysis Patients: A Case-series

Start date: April 2009
Phase: N/A
Study type: Interventional

Purpose: Hemodialysis-dependent patients with an end-stage renal disease (ESRD) suffer from a number of distressing symptoms, such as pain, poor mental health, fatigue, sleep disturbance and pruritus. These negatively influence health-related quality of life in ESRD patients, and some of them result in increased mortality and hospitalization. Acupuncture is a widely employed treatment on several chronic disease or condition. Adjunctive use of acupuncture with conventional treatment could be a possible therapeutic option to establish an optimal care for ESRD patients who experiences co-morbid conditions or complications of hemodialysis. Due to its non-pharmacologic feature, the effects of acupuncture without involving altered pharmacokinetics and drug-interactions in hemodialysis patients, might be another strong point compared to other pharmacological interventions. However, little information is available for the effects and the safety of acupuncture for symptomatic care of hemodialysis patients. Thus, the investigators propose whether acupuncture could be a effective and safe therapeutic modality for a number of patient-reported symptoms in hemodialysis-dependent patients with ESRD.

NCT ID: NCT00852787 Active, not recruiting - Hypertension Clinical Trials

Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease

Start date: April 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine the effects of the digibind drug on hemodialysis patients with high blood pressure. Digibind is used to treat toxicity from digoxin and digoxin-like molecules which may contribute to high blood pressure.

NCT ID: NCT00850252 Completed - Hemodialysis Clinical Trials

Use of a Lifeline Graft in the A-V Shunt Model

Start date: September 2004
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess the safety and efficacy of a completely autologous and completely biological tissue engineered blood vessel (TEBV) called Lifeline™ used as an arteriovenous fistula for dialysis access.

NCT ID: NCT00811109 Completed - Hemodialysis Clinical Trials

HEMOTOL: Efficacy and Safety of Hemodialysis On-line Monitoring Devices on Hemodynamic Stability in Intensive Care Unit

HEMOTOL
Start date: December 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this randomized controlled study is to compare the effects of different new dialysis on-line monitoring devices on hemodynamic stability during intermittent hemodialysis in critically ill patients with acute kidney injury.

NCT ID: NCT00776750 Completed - Hemodialysis Clinical Trials

Influenza Vaccination in Hemodialysis Patients and Renal Transplant Recipients

Start date: September 2003
Phase: Phase 4
Study type: Interventional

Disturbances of acquired immunity are considered to be responsible, at least partly, for the high infection rate and inadequate response to vaccinations observed in hemodialysis (HD) patients and renal transplant recipient (RTR). The present prospective trial aims at (a) evaluating the immunogenicity of a standard influenza vaccine in HD and RTR patients and (b) at identifying determinants of the immune response.