Evaluation of Curcumin's Effect on Inflammation in Hemodialysis Patients

Status Completed

Clinical Trial Summary

Programmed ingestion of turmeric has no adverse effects and reduces plasma level of hs-CRP, IL-6 and TNF-α accompanying with increases albumin levels in hemodialysis patients. Turmeric can be considered as an effective anti-inflammatory supplement in hemodialysis patients.

Clinical Trial Description

Hemodialysis patients over 18 years were recruited after fulfilling the inclusion criteria.Seventy-one hemodialysis patients were randomized into two groups: the trial group (n =35 ) and the controls (n =36 ); a randomization numeric table was used for allocation sequence . Trial group received turmeric and control group received placebo for 12 weeks. Biochemical determinations included levels of serum albumin (Alb), potassium (K) ,blood urea nitrogen (BUN), serum creatinine (Cr), IL-6 level, TNF- α , and liver function tests and hs-CRP at the start and end of the study were measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03144882
Study type	Interventional
Source	Shahid Beheshti University of Medical Sciences
Contact
Status	Completed
Phase	N/A
Start date	February 2, 2015
Completion date	February 2, 2017

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