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Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis — BP-AVALVE  

Heart Failure Clinical Trial

Official title:
Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis

Clinical Trial Summary

The aim of this study is to investigate the effect of strict blood pressure control versus conventional care in patients with asymptomatic moderate to severe aortic valve stenosis. The study is a randomized (1:1), open label, controlled intervention trial. Hypothesis: 1. Strict BP control for 12 months reduces the progression of LV remodelling compared to conventional treatment. 2. Strict BP control for 2 years reduces the increase in aortic valve calcification and LV remodelling compared to conventional treatment. 3. Strict BP reduction for up to 10 years reduces the need for aortic valve replacement and cardiovascular events compared to conventional care.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04613193
Study type Interventional
Source Aarhus University Hospital
Contact Henrik Wiggers, MD, PhD
Email henrikwiggers@dadlnet.dk
Status Recruiting
Phase N/A
Start date March 1, 2019
Completion date June 1, 2031
View Details
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