Heart Failure Clinical Trial
— MAGICOfficial title:
Investigation of Myocardial Function and Vascular Adaptation in Association With Genotype in Marathon Runners
Verified date | March 2016 |
Source | Technische Universität München |
Contact | n/a |
Is FDA regulated | No |
Health authority | Germany: Technical University of Munich |
Study type | Interventional |
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with genotype/polymorphisms. We aim to investigate the effects of extreme endurance exercise on the cardiovascular system. Furthermore, the role of the inflammatory response and adaptive mechanisms of the vasculature are examined. Subclinical injuries to the myocardium and vascular wall are being investigated.
Status | Completed |
Enrollment | 162 |
Est. completion date | August 2014 |
Est. primary completion date | March 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 30 Years to 60 Years |
Eligibility |
Inclusion Criteria: - men aged 30-60 years Exclusion Criteria: - manifested heart disease - insulin dependent diabetes mellitus - multi drug therapy - GFR<60ml/min. |
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Germany | Department of Prevention and Sports medicine | Munich | Bavaria |
Lead Sponsor | Collaborator |
---|---|
Technische Universität München |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | E/A ratio | pre-, post-, one day follow-up | Yes | |
Secondary | LV twist | pre-, post-, one day follow-up | Yes |
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