Heart Failure Clinical Trial
Official title:
The Atlanta Cardiomyopathy Consortium
Heart failure is a very common cause of hospital admission and there are half a million new cases diagnosed each year in the United States. While some important progress has been made over the last two decades for the treatment of heart failure, there still remains a critical need for further advances in our understanding of this disease in order to significantly improve patient outcomes. Large numbers of heart failure patients need to be studied over time to allow scientists to investigate those factors that influence the responses to therapy.
In this study information will be collected on patients with heart failure and their
progress and outcomes will be followed over time. The aim is to understand the natural
history, risk factors for improvement or progression, and determinants of response to
therapy for heart failure. Of interest are many aspects of heart failure including genetic
influences, quality of life issues, how individuals cope with feelings about having heart
disease, and how they manage their day-to-day symptoms etc.. A database will be created of
approximately 1,000 heart failure patients from Emory, Emory University Hospital Midtown,
Wesley Woods, Grady, and the VA Medical Center.
This is strictly an observational study and subjects will not be receiving any experimental
therapy nor will their routine medical care be affected in any way. Data to be collected
includes:
1. Medical history of the patient
2. Medical history on the patient's family
3. Survey data including health behaviors & psychosocial variables
4. Blood & urine samples
5. EKG
6. Six minute Walk Test
7. Hand grip strength
After collecting data, a variety of statistical tests will be run to analyze factors that
influence heart failure patients' responses to treatment. The results of this analysis will
be used to optimize therapy for future heart failure patients.
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