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Clinical Trial Summary

To determine the safety and efficacy of an intracoronary injection of adenovirus 5 encoding human adenylyl cyclase 6 (RT-100) in patients with heart failure with reduced left ventricular ejection fraction (HFrEF) in a Phase 3 clinical trial.


Clinical Trial Description

This is a randomized, placebo-controlled, double-blinded Phase 3 clinical trial using a one-time intracoronary injection of Ad5.hAC6 (or placebo) to determine safety and efficacy in patients with documented HFrEF. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03360448
Study type Interventional
Source Renova Therapeutics
Contact Richard McCloskey, MD
Phone 858-461-1837
Email mac@renovatherapeutics.com
Status Not yet recruiting
Phase Phase 3
Start date September 2018
Completion date September 2022

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