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Clinical Trial Summary

Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either oral sodium nitrite capsules or oral placebo capsules through the training period. Study drug is administered 3 times daily during daytime hours with one of these doses being 30 minutes prior to onset of ET sessions throughout 10 weeks of the12 week trial. The objective is to determine if the oral sodium nitrite improves the clinical responses and tolerability of ET.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02713126
Study type Interventional
Source Mayo Clinic
Contact Amanda M Biddle, RN
Phone 507-538-5428
Email biddle.amanda@mayo.edu
Status Recruiting
Phase Phase 2
Start date September 2016
Completion date December 2020

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