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NCT03232671 Clinical Trial

Role of Macrophage Migration Inhibitory Factor (MIF) in Heart Failure

Heart Diseases Clinical Trial

Official title:
Role of Macrophage Migration Inhibitory Factor (MIF) in Heart Failure

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03232671
Other study ID # 15-6529-BO
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 2016
Est. completion date September 1, 2020

Study information
Verified date November 2022
Source University Hospital, Essen
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Evaluating the additional value of Macrophage Migration Inhibitory factor (MIF) in cardiovascular diseases when assessed in clinical routine.

Recruitment information / eligibility
Status Completed
Enrollment 180
Est. completion date September 1, 2020
Est. primary completion date April 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: All patients presenting with symptoms of heart failure to the West-German Heart and Vascular Center according to the definition of the ESC 2016. - Patients fulfilling criteria for the diagnosis of HFrEF - Patients fulfilling criteria for the diagnosis of HFpEF - Patients fulfilling criteria for the diagnosis of HFmrEF - Patients presenting with dyspnea according to the NYHA classification I-IV, elevated BNP/NT-proBNP levels and echocardiographic findings of heart failure. Exclusion Criteria: - Age < 18 years - Patients with symptoms of heart failure without fulfilling the criteria of the ESC guidelines 2016 - Denial to participate

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• MIF ELISA
Blood sample

Locations
Country Name City State
Germany University Hospital of Essen Essen NRW

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Essen

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary 180 days mortality 180 days
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