Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes)

Heart Disease Congenital Clinical Trial

Official title:
Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease

Status Completed

Clinical Trial Summary

Approximately 400 Congenital heart disease patients will participate in the research study which will include one or more research visits for neurodevelopmental testing, brain MRI, and collection of medical history including previously collected genetic sequencing results. The investigators will explore the association between genetic variants, neurodevelopmental deficits, and brain MRI endophenotype. Analyses will compare groups with and without deleterious de novo mutations.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03070197
Study type	Observational
Source	Children's Hospital Medical Center, Cincinnati
Contact
Status	Completed
Phase
Start date	September 18, 2017
Completion date	June 29, 2020

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT05926661` - Support Tool for Families of High-Risk Children With Heart Disease During Hospital Admission and After Discharge	N/A
Completed	`NCT04442685` - The Swiss Registry for Heart Diseases in Children Living in Switzerland. SPHC
Active, not recruiting	`NCT04667455` - Improving Care for Children With Congenital Heart Disease.	N/A