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Heart Arrest clinical trials

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NCT ID: NCT00329563 Completed - Cardiac Arrest Clinical Trials

Pilot Community Clinical Study of Hypothermia in Cardiac Arrest

Start date: November 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The overall goal of this study is to determine the feasibility of initiating hypothermia in cardiac arrest patients as soon as possible in the field. In this pilot study we will randomize 125 patients after return of spontaneous circulation (ROSC) to hypothermia with rapid infusion of 2 liters of 4oC Normal Saline IV solution over 20 to 30 minutes, IV sedation and muscle paralysis or to standard of care following ROSC. The primary objectives of this study will be to determine whether temperature of 33-34oC can be achieved and maintained using this strategy. The primary outcome measures will include: temperature changes of the patients at time of admission to the hospital. Secondary analysis will include determining if the proportion of patients discharged from the hospital is increased in the group receiving hypothermia. If this initial pilot study can demonstrate feasibility in achieving and maintaining hypothermia, a larger randomized clinical trial to test the hypothesis that hypothermia initiation in the field will increase the proportion of patients surviving following cardiac arrest will be planned.

NCT ID: NCT00312273 Completed - Cardiac Arrest Clinical Trials

Aminophylline in Bradyasystolic Cardiac Arrest

Start date: January 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.

NCT ID: NCT00308815 Recruiting - Cardiac Arrest Clinical Trials

Comparison of Manual Cardiopulmonary Resuscitation (CPR) Versus Automatic CPR Machine During Ambulance Transport.

Start date: January 2005
Phase: N/A
Study type: Interventional

This is a randomized controlled prospective study which assigned patient to receive manual CPR or automatic CPR machine use. The quality and efficacy between manual CPR and machine CPR will be evaluated.

NCT ID: NCT00300703 Completed - Cardiac Arrest Clinical Trials

OPALS Cardiac Arrest Database (OCAD)

Start date: January 2006
Phase: N/A
Study type: Observational

To provide the infrastructure to answer prehospital research questions posed by scientists at academic health science centers and policy makers at multiple levels of government.

NCT ID: NCT00292032 Completed - Cardiac Arrest Clinical Trials

Registry of Unexplained Cardiac Arrest

Start date: May 2004
Phase:
Study type: Observational

The CASPER will collect systematic clinical assessments of patients and families within the multicenter Canadian Inherited Heart Rhythm Research Network. Unexplained Cardiac Arrest patients and family members will undergo standardized testing for evidence of primary electrical disease and latent cardiomyopathy along with clinical genetics screening of affected individuals based on an evident or unmasked phenotype.

NCT ID: NCT00282373 Completed - Cardiac Arrest Clinical Trials

Induction of Mild Hypothermia in Resuscitated Cardiac Arrest Patients

Start date: November 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objectives of this study are to determine the safety and feasibility of inducing mild hypothermia using a non-invasive thermoregulatory device, the Medivance Arctic Sun Temperature Management System, in patients resuscitated after cardiac arrest.

NCT ID: NCT00228293 Terminated - Cardiac Arrest Clinical Trials

Assessing CPR Quality During In-Hospital Cardiac Arrest

Start date: December 2002
Phase: Phase 2/Phase 3
Study type: Interventional

Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during sequential in-hospital cardiac arrests at the University of Chicago Hospitals. Using an audio feedback system linked to this device, we are studying whether such audio feedback improves CPR quality when provided to rescuers trained in the use of the device.

NCT ID: NCT00226681 Completed - Clinical trials for Sudden Cardiac Arrest

Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD)

Start date: September 1999
Phase: Phase 1
Study type: Interventional

To determine if an education and support nursing intervention program helped sudden cardiac arrest survivors adjust to the event and to getting an ICD

NCT ID: NCT00219687 Completed - Heart Arrest Clinical Trials

Dispatcher-Assisted Resuscitation Trial (DART)

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.

NCT ID: NCT00219674 Completed - Clinical trials for Myocardial Infarction

At-Home Automated External Defibrillator (AED) Training Study

Start date: July 2004
Phase: Phase 2
Study type: Interventional

The purpose of the research is to determine the best automated external defibrillator (AED) training approach for high-risk patients and their family members with regard to AED skills retention and psychological adjustment.