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Heart Arrest clinical trials

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NCT ID: NCT06299969 Recruiting - Clinical trials for Out-Of-Hospital Cardiac Arrest

Feedback Intervention and Treatment Trial in Patients With Out-of-Hospital Cardiac Arrest

FITT-OHCA
Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

The trial collects and analyzes data from Cardiac Arrest Centres in patients with out-of-hospital cardiac arrest (OHCA).

NCT ID: NCT06275984 Not yet recruiting - Clinical trials for Cardiopulmonary Arrest With Successful Resuscitation

Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers.

EFORCP
Start date: June 2024
Phase: N/A
Study type: Interventional

Background: Cardiorespiratory arrest (CPA) occurs when there is a cessation of cardiac mechanical activity, typically diagnosed by the absence of consciousness, pulse, and breathing. Actions taken in response to CPA include recognizing the condition and promptly notifying emergency medical services, initiating Cardiopulmonary Resuscitation (CPR) maneuvers, and employing an Automated External Defibrillator (AED). Survival rates are directly influenced by the time elapsed between CPA onset and the initiation of CPR maneuvers, as well as the quality of these interventions Hypotheses: Online education in CPR maneuvers is an effective and efficient tool for training individuals from the general population on how to respond to cardiac arrests Objectives: The primary aim of this study is to assess the efficacy of online CPR and AED training within the general population of the province of Tarragona. Specific objectives include: 1) evaluating participants' theoretical and practical CPR skills in the short and medium term following online training, and 2) exploring the experiences of individuals who have completed the online training and simulation sessions using qualitative methodology. Methodology:This study will unfold in several phases: 1) Online CPR-AED training and assessment of theoretical knowledge acquisition; 2) Evaluation of acquired practical CPR skills (know-how) within a simulation environment, conducted on a subset of the population completing phase 1;3)Analysis of the experiences of a subset of individuals who have participated in the preceding two phases, employing qualitative methodology Variables and determinations:The primary response variable for phase 1 will be the difference in scores obtained from the online questionnaire between the final (post-training) and initial (pre-training) assessments. In phase 2, the main variable will be the pass/fail categorization of scores in the simulation. This evaluation will be conducted by two members of the Advanced Clinical Simulation Unit at Joan XXII Hospital using a predefined checklist. Throughout the various phases of the study, socio-demographic data and course performance data will be taken into account Expected results: The research team for this study aims to ascertain the efficacy and effectiveness of online CPR-AED training within the general population. Furthermore, the study aims to provide evidence regarding the optimal duration and frequency for repeating such training. Applicability and Relevance: This proposal advocates for a significant and innovative project, given the dearth of literature on this topic. While there are existing indications and studies on CPR-AED training among specific populations such as students and healthcare professionals, the presented proposal seeks to broaden the scope of training to encompass the general population.

NCT ID: NCT06251609 Not yet recruiting - Opioid Overdose Clinical Trials

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest

NOPACA
Start date: January 1, 2025
Phase: Phase 2
Study type: Interventional

The investigator's long-term goal is to conduct Naloxone for Opioid Associated out of Hospital Cardiac Arrest (NOPACA), a randomized, double blind, controlled trial to determine the efficacy of naloxone vs. placebo in Opioid Associated out of Hospital Cardiac Arrest. The investigative team plan to randomize patients in OHCA to early naloxone administration vs. placebo after initial resuscitation and measure ROSC and survival. Challenges to designing NOPACA include uncertainty regarding: 1) the available pool of participants and number of EMS agencies needed to meet enrollment targets; 2) acceptability among patients, EMS and Emergency Medicine provider stakeholders, and 3) estimates of the study outcomes needed for sample size estimates. Toward obtaining the necessary information to design NOPACA, the investigators propose a pilot RCT of participants at high risk for OA-OHCA to verify a reasonable recruitment rate; treatment fidelity and acceptability; and adequate retention and measurement of outcomes at follow up. The investigators propose incorporating hypothesis testing of the feasibility outcomes to determine progression to a definitive trial.

NCT ID: NCT06249893 Recruiting - Clinical trials for Cardiac Arrest, Out-Of-Hospital

Feasibility of Doppler Ultrasound for Pulse Detection in Out-of-Hospital Cardiac Arrest Patients

Start date: January 4, 2024
Phase:
Study type: Observational

The goal of this prospective observational study is to investigate the feasibility of using doppler point-of-care ultrasound on the femoral artery with a portable device to assess the presence of a pulse in patients suffering from cardiac arrest in the out-of-hospital environment. The main question is how often researchers are successful in acquiring the necessary ultrasound signal in the out-of-hospital environment.

NCT ID: NCT06249035 Not yet recruiting - Cardiac Arrest Clinical Trials

Feasibility of TEE During Cardiac Arrest in Dutch Emergency Departments

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this feasibility study is to learn if Dutch ED providers are able to use transesophageal echocardiography during cardiac arrest. The main question it aims to answer is: • are the ED providers able to determine the area of maximal compression of the heart using TEE

NCT ID: NCT06229418 Not yet recruiting - Cardiac Arrest Clinical Trials

Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural America

RESTORe-CARE
Start date: January 1, 2025
Phase: N/A
Study type: Interventional

The overall goal of this project is to design, develop, and pilot test an emergency healthcare drone delivery system suitable for rural communities that can deliver AEDs to out-of-hospital cardiac arrest (OHCA) locations more rapidly than can be achieved with current first responder and EMS systems. The goal is to determine whether this method of AED delivery can be achieved rapidly enough to justify a future clinical trial directly testing its ability to improve OHCA survival.

NCT ID: NCT06226246 Recruiting - Cardiac Arrest Clinical Trials

Evaluation of Effectiveness of Virtual Reality-based Dispatcher Assisted Cardiopulmonary Resuscitation Training

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This study aims to compare the effect of conventional cardiopulmonary resuscitation (CPR) training and CPR training with added virtual reality (VR) on trainee self-efficacy.

NCT ID: NCT06218329 Recruiting - Clinical trials for Cardiology, Critical Care Medicine, Emergency Medical Service

TIMECARD(TaIwan Network of Post-arrest ManagEment for CARDiac Arrest)IIRegistry

TIMECARDII
Start date: January 1, 2022
Phase:
Study type: Observational

This study aims to collect the post-cardiac arrest patients with ICU admission.

NCT ID: NCT06207942 Recruiting - Clinical trials for Cognitive Impairment

Stepcare Extended Follow-up Substudy

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

To provide detailed information on long-term outcomes in relation to potential neuroprotection and improvements in recovery for different targets of sedation, temperature, and pressure management in post out of hospital cardiac arrest survivors at 6 and 12 months. In addition, the impact of caring for a post OHCA survivor will be explored.

NCT ID: NCT06207201 Recruiting - Cardiac Arrest Clinical Trials

Discover In-Hospital Cardiac Arrest

Discover IHCA
Start date: October 16, 2023
Phase:
Study type: Observational [Patient Registry]

The Discover In-Hospital Cardiac Arrest (IHCA) study is a multicenter, prospective observational study aimed at better understanding variations in practice for the post-in-hospital cardiac arrest patient.