Healthy Clinical Trial
Official title:
Diverse Ancestry Study in Inflammatory Bowel Disease
Objective: To use clinical, genetic and genome analysis to better understand and define the genetic and environmental factors that contribute to IBD in diverse ancestries: African, African American, Black, Afro-Caribbean, Afro-Latino/a/x, Latino/a/x, Hispanic, or any other Black or Latin or indigenous ancestry.
Status | Recruiting |
Enrollment | 150 |
Est. completion date | September 2027 |
Est. primary completion date | May 2027 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Subject must self-identify as African, African American, Black, Afro-Caribbean, Afro-Latino/a/x, Latino/a/x, Hispanic, or any other Black or Latin or indigenous ancestry - Subjects: diagnosed with Inflammatory Bowel Disease (Crohn's disease, ulcerative colitis, IBD-undetermined) - Available medical records to confirm IBD diagnosis (Crohn's disease, Ulcerative colitis, IBD undetermined (IBD-U)) - Healthy controls: no personal history of IBD, no family history of IBD, no history of unexplained chronic diarrhea/blood in stool/anemia/abdominal pain/weight loss - Any age Exclusion Criteria: - Doesn't self-identify as African, African American, Black, Afro-Caribbean, Afro-Latino/a/x, Latino/a/x, Hispanic, or any other Black or Latin or indigenous ancestry - Subjects with other gastrointestinal conditions not meeting the above IBD or Healthy Control criteria |
Country | Name | City | State |
---|---|---|---|
Canada | Sinai Health System | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
Mount Sinai Hospital, Canada | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Genetics studies in diverse ancestries | Whole Exome Sequencing (+/- other sequencing) is planned to assess genetic diversity in diverse populations. | 2022-2027 |
Status | Clinical Trial | Phase | |
---|---|---|---|
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