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Real-time Neurofeedback Training of Fronto-limbic Regions Functional Connectivity

Healthy Clinical Trial

Official title:
Real-time Neurofeedback Training of Fronto-limbic Areas Functional Connectivity to Reduce Arousal

Clinical Trial Summary

This is randomized active-sham group controlled between-subject real-time fMRI neurofeedback trial aimed at modulating the ventromedial prefrontal cortex (vmPFC)-amygdala pathway to control subjective anxiety and arousal.

Clinical Trial Description

The present randomized active-sham group controlled between-subject real-time fMRI neurofeedback trial aims at determining if (1) subjects can gain volitional control over the vmPFC-amygdala pathway involved in implicit emotion regulation and arousal by means of connectivity informed neurofeedback, (2) whether the training has specific effects on the behavioral and psychophysiological arousal level, and (3) or the amygdala or the vmPFC connectivity, respectively. The present project will determine the efficacy of the modulation of the vmPFC-amygdala functional connectivity pathway using vmPFC-amygdala upregulation (n = 25 subjects) compared to a sham control condition (targeting pathways not involved in emotion regulation, n = 20). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06033053
Study type Interventional
Source University of Electronic Science and Technology of China
Contact Benjamin Becker, Ph.D.
Phone +86-28-61830670
Email ben_becker@gmx.de
Status Recruiting
Phase N/A
Start date September 1, 2023
Completion date March 31, 2025
View Details
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