Healthy Clinical Trial
Official title:
Double-blind, Randomized, Controlled, Three-way Cross-over Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose and Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period. In addition, tolerability and safety of gum acacia (FibregumTM) will be assessed.
Gum arabic is a heteropolysaccharide (molecular weight 350-850 kDa) harvested from Acacia
seyal or Acacia senegal. It is highly soluble and broadly used in numerous solid and liquid
food matrices.
For the assessment of non-digestible carbohydrates as dietary fiber, it is eminent to
demonstrate that its consumption is related to a specific beneficial physiological effect
shown in an appropriate clinical study. The aim of the present trial was to expand the
clinical evidence with respect to beneficial effects of gum acacia on post-prandial blood
glucose levels, post-prandial insulin levels and prospective ad libitum food intake, in
normal-weight and overweight subjects.
The present double-blind, randomized, controlled, three-way cross-over study was to evaluate
the effect of gum acacia versus no treatment on post-prandial glucose (PPG) levels in
normal-weight and overweight subjects during a 2-7 weeks intervention period.
Additionally, post-prandial insulin (PPI) levels, prospective ad libitum food intake, as well
as the safety and tolerability of gum acacia were assessed.
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