Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Healthy Clinical Trial

Official title:

Acute Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03180814
• Other study ID #: WBV on autonomic function
• Status: Completed
• Phase: N/A
• First received: March 21, 2017
• Last updated: December 29, 2017
• Start date: July 31, 2017
• Est. completion date: December 30, 2017

Study information

• Verified date: December 2017
• Source: Universidade Federal de Pernambuco
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: December 30, 2017
• Est. primary completion date: August 31, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Elderly individuals aged between 60 and 80 years

• Young individuals aged between 18 and 30 years

• Able to walk without assistance

• Good understanding to perform the proposed procedures

• Sedentary or low active

Exclusion Criteria:

• Body Mass Index (BMI) > 35Kg/m2

• Systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg (at rest)

• Difficulty adapting to the whole body vibration

• Smoking

• Neuromuscular or degenerative disorders

• Neurological diseases

• Cardiopulmonary comorbidities

• Cardiac arrhythmias

• Osteoarticular disorders

• Use of hormone replacement therapy

• Use medications or supplements known to affect cardiovascular parameters

• Labyrinthitis

Related Conditions & MeSH terms

• Aging
• Healthy

Intervention

Other:
• Whole Body Vibration
A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.

Locations

Country	Name	City	State
Brazil	Federal University of Pernambuco	Recife	Pernambuco

Sponsors (1)

Lead Sponsor	Collaborator
Universidade Federal de Pernambuco

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Autonomic Function	Heart rate variability will be assessed from 3-channel holter	Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes
Secondary	Sympathetic modulation	Sympathetic modulation will be assessed from 3-channel holter	Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes
Secondary	Parasympathetic modulation	Parasympathetic modulation will be assessed from 3-channel holter	Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes
Secondary	Sympathovagal Balance	Sympathovagal Balance will be assessed from 3-channel holter	Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes
Secondary	Heart Rate	Non-invasive measures will be assessed from 3-channel holter	Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes
Secondary	Blood pressure	Non-invasive measures of brachial blood pressure	Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes
Secondary	Peripheral oxygen saturation	Non-invasive measures will be assessed from pulse oximeter	Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes
Secondary	Adverse effects	Adverse effects reported by volunteers	Change from Baseline at 20 minutes