Healthy Clinical Trial
Official title:
The Change of Tissue Oxygen Saturation Measured by Dynamic Near Infrared Spectroscopy Following Volatile Anesthesia in Healthy Population
General anesthesia can affect tissue oxygen saturation and microcirculatory reactivity.
However, the differences in microcirculation caused by anesthetic methods have not been well
studied. Near-infrared spectroscopy (NIRS) measures peripheral tissue oxygen saturation
noninvasively and can be used in conjunction with vascular occlusion (VOT) experiments. The
purpose of this study was to examine the changes in NIRS derived tissue oxygen saturation
(StO2) and microcirculatory reactivity by VOT after inhalation anesthesia in healthy
population.
This prospective, observational study will be performed on 60 healthy patients who had
undergone elective surgery under volatile general anesthesia. The investigators measure StO2
and microvascular reactivity using NIRS combined with vascular occlusion test (VOT). The
parameters were performed twice per patient, before and after the induction of anesthesia.
Occlusion slope and recovery slope during VOT will be compared before and after anesthesia.
Moreover, the changes depend on the age will be analyzed.
This prospective observational study was performed on 60 patients without comorbidities who underwent elective surgery under general anesthesia. Before and after the induction of anesthesia, StO2 monitoring and VOT were performed to investigate the effect of anesthesia on microcirculation. To investigate the effect of age on microcirculation, the patients were divided into two different groups, young (< 65 yrs) and old (> 65 yrs) groups, and the VOT-derived parameters and hemodynamics between two groups were compared. ;
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