Healthy Clinical Trial
Official title:
Inspiratory Resistive Loading and Diaphragm Fatigue in Healthy Individuals and Individuals With Recurrent Low Back Pain
Verified date | July 2012 |
Source | Katholieke Universiteit Leuven |
Contact | n/a |
Is FDA regulated | No |
Health authority | Belgium: Ethics Committee |
Study type | Observational |
The aim of the study is to clarify whether specific loading of the inspiratory muscles induces contractile fatigue of the diaphragm muscle in healthy individuals and individuals with recurrent low back pain.
Status | Completed |
Enrollment | 20 |
Est. completion date | June 2012 |
Est. primary completion date | April 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria individuals with low back pain: - Age: 18-35 years old - At least 1 year of low back pain with/without referred pain in buttock/thigh - At least 3 episodes of disabling low back pain - At least a score of 20% on the Oswestry Disability Index - Willingness to sign the informed consent Inclusion Criteria healthy individuals: - Age: 18-35 years old - No history of low back pain - A score of 0% on the Oswestry Disability Index - Willingness to sign the informed consent Exclusion Criteria: - History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant - One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder, respiratory disease, pregnancy - Radicular symptoms - Not Dutch-speaking - Strong opioids - Neck pain - Smoking history |
Observational Model: Case Control, Time Perspective: Cross-Sectional
Country | Name | City | State |
---|---|---|---|
Belgium | Katholieke Universiteit Leuven | Leuven |
Lead Sponsor | Collaborator |
---|---|
Katholieke Universiteit Leuven | Universitaire Ziekenhuizen Leuven |
Belgium,
Hermans G, Agten A, Testelmans D, Decramer M, Gayan-Ramirez G. Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study. Crit Care. 2010;14(4):R127. doi: 10.1186/cc9094. Epub 2010 Jul 1. — View Citation
Janssens L, Brumagne S, Polspoel K, Troosters T, McConnell A. The effect of inspiratory muscles fatigue on postural control in people with and without recurrent low back pain. Spine (Phila Pa 1976). 2010 May 1;35(10):1088-94. doi: 10.1097/BRS.0b013e3181bee5c3. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | transdiaphragmatic pressure | transdiaphragmatic pressure measurement in response to bilateral anterior magnetic phrenic nerve stimulation before and after an inspiratory resistive loading protocol | 18 months | Yes |
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