Changes in Brain Tissue Pulsatility With Musical Stimuli

Healthy Clinical Trial

— M-PULSE  

Official title:

Changes in Brain Tissue Pulsatility With Musical Stimuli

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03867422
• Other study ID #: RIPH3-RNI19-M-PULSE
• Status: Completed
• Start date: April 2, 2019
• Est. completion date: April 26, 2019

Study information

• Verified date: August 2019
• Source: University Hospital, Tours
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Music Perception is well known to elicit emotions and neuronal activations. Changes in the cerebrovascular physiology have also been found in emotional tasks but only few studies have investigated markers of cerebrovascular physiology in a music task and no study has used the Ultrasound method of Tissue Pulsatility Imaging (TPI) in a music task. The use of TPI to measure reactivity of Brain Tissue Pulsatility Imaging (BTP) could further elucidate the cerebral basis of music perception.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: April 26, 2019
• Est. primary completion date: April 26, 2019
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• more or equal 18 years-old and less or equal 45 years-old

• no known hearing problem

Exclusion Criteria:

• professional musician

• history of neurologic, psychiatric or cadiologic disease

• treatment which could impact parameters of brain tissue pulsatility and peripheral nervous system

• opposition to use the data

Related Conditions & MeSH terms

• Healthy

Locations

Country	Name	City	State
France	DESMIDT	Tours

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Tours

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	amplitude of variations in brain tissue pulsatility	in micrometers	Baseline
Secondary	heart rate	beat by minute	Baseline
Secondary	breathing rate	Frequency	Baseline
Secondary	skin conductance	in milliVolt	Baseline
Secondary	score of barcelona music reward questionnary (BMQR)	BMQR: Barcellona Music Reward Questionnaire for the evaluation of musical anhedonia; Only the total score of musical reward will be reported; for total score, minimum value is 20, maximum value is 100. Values under 40 represent low values in the overall score; values above 60 indicate high values in the overall score; High global score (>60) represents a better outcome; low global score (<40) represents a worse outcome, notably an impairment in music reward processing; The overall score is computed by adding raw scores of the items (except for items 2 and 5, which need to be reversed).	Baseline