Healthy Clinical Trial
Official title:
Impact of Interdental Brushing on the Evolution of Supra-gingival Bacterial Flora in Healthy Subjects Aged 18 to 35 Years (BACTERIB)
In France, two-thirds of adults over 35 years of age have at least a periodontal disease. The
etiology is the accumulation of dental plaque, especially in interdental spaces. The cleaning
of interdental spaces is particularly complex. This accumulation of dental plaque is at the
origin of a modification of the bacterial flora in favor of periodontopathogenic bacteria.
These pathogens can induce within the periodontal tissues an immune and inflammatory reaction
that cause tissue degradation. The majority of studies focus on people over 30 years of age
with gingivitis or periodontitis. However, young adults, in whom the initial or even
reversible stages of periodontal disease are the most frequent, should be the preferred
target of preventive measures for this pathology.
The main objective of this study is to quantify, in healthy patients, the evolution of the
supragingival bacterial flora, in the interdental spaces, following the daily passage of
brushes with the adapted diameter and single passage. The secondary objective is to evaluate
the qualitative change in the bacterial flora (proportions of periodontal bacteria /
commensal bacteria) following the interdental cleaning.
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