Glycemic Index of Table Grape Varietals

Healthy Clinical Trial

Official title:

Investigation of the Glycemic Index of Table Grape Varietals

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03248609
• Other study ID #: 1086796
• Status: Completed
• Phase: N/A
• Start date: July 31, 2017
• Est. completion date: June 4, 2018

Study information

• Verified date: April 2019
• Source: University of California, Davis
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals or grape juice, compared to a standard amount of glucose.

Description:

The study aims to investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals, compared to a standard amount of glucose. The study also aims to evaluate a new grape varietal, compared to other common table grapes, with regard to glycemic index and metabolic response related to inflammation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: June 4, 2018
• Est. primary completion date: June 4, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years to 75 Years

Eligibility

Inclusion Criteria:

• Healthy men and women

• 21-75 years of age

• BMI range 20-35

Exclusion Criteria:

• adults unable to consent, individuals who are not yet adults (children), pregnant women, and prisoners.

• BMI of >35 or morbid obesity.

• Diagnosed type 1 or 2 diabetes, fasting blood glucose of >125 mg/dl, or reported use of medications or supplements known to affect glucose metabolism (insulin, sulfonylureas, metformin, glucosidase inhibitors, thiazolidinedione, insulin sensitizers, GLP-1 mimetics).

• Medications known to affect gastrointestinal motility (prokinetic agents such as reglan).

• Renal, liver, pancreatic or cardiovascular disease, uncontrolled hypertension of > 160/90, inflammatory bowel disease, disorders of esophageal and gastrointestinal motility, previous gastric resection or restriction procedures, autoimmune or immunologic disorders, anemia, breastfeeding women

• Food allergy to grapes, or inability to tolerate gluten (celiac disease).

• Poor venous access.

• Smoking, illicit drug use, consuming >7 alcoholic drinks per week.

• Weight gain or loss of > 5 kg within the prior 6 months.

• Unwillingness to adhere to study protocol.

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• Milano grapes
Milano grapes to test post-prandial glycemic response
• Table grapes
Table grapes to test post-prandial glycemic response
• Grape juice
Grape juice to test post-prandial glycemic response
• Glucose beverage
Standardized glucose beverage to test post-prandial glycemic response

Locations

Country	Name	City	State
United States	University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility)	Davis	California

Sponsors (1)

Lead Sponsor	Collaborator
University of California, Davis

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Glycemic Index	The post-prandial glucose and insulin responses in healthy individuals to glucose containing foods or beverages.	3 hours