Healthy Individuals Clinical Trial
Official title:
Drug Use During a Very Long Distance Mountain Trail: a Study Using Automated Urine Collection
Hypothesis: To verify whether the use of drugs, in particular performance-enhancing drugs, is
prevalent amongst participants in a very long distance mountain trail.
Primary objective : To qualify and quantify drug use amongst participants in a very long
distance mountain trail, by targeting the molecules most likely used by the runners.
Introduction : very long distance mountain trail which is particularly demanding for the
organism. This kind of competition is likely to have an impact on the athlete's health and /
or physical integrity. It is assumed that many participants may use medication in an attempt
to i) prevent and /or treat medical conditions induced by prolonged muscular exercise, and
ii) delay fatigue and improve physical and/or psychological capacities. Beyond ethical and
regulatory considerations, such practice in this isolated environment is not without health
risks. However, to our knowledge, there is no objective data on medication use during very
long distance mountain trails.
Methodology : Individual urine samples from male competitors participating in a very long
distance mountain trail and using temporary urinals near the starting line will be collected
within three hours before departure, anonymously, blindly, using hidden automated samplers.
Simultaneously with automated urine sampling, demographic data (age class, ranking class,
geographical area of residence, performance class over the year) will be collected
anonymously via an automated system detecting the runners' electronic bibs. The
quantification of different classes of drugs in the urine samples will be performed by World
Anti-Doping Agency-accredited laboratories using liquid chromatography, mass spectrometry and
/ or gas chromatography. The classes of molecules sought will be the following: most common
non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, stimulants, narcotics,
anabolic agents, metabolic modulators, cannabinoids, beta2-agonists, beta-blockers,
diuretics, benzodiazepines. A questionnaire about drug use before/during the race and using
the randomized response technique (RRT) will be proposed online, anonymously to female and
male participant after the competition.
Expected results : drug use is frequent amongst participants in a very long distance mountain
trail. Drug use prevalence measured from automated urine collection is higher than that
obtained from the RRT questionnaire.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT06044896 -
Physiology of Body Lateralization on Regional Lung Ventilation Study
|
N/A | |
Completed |
NCT02101801 -
Urine Drug Levels Related to Source of Water for Irrigation for Vegetable Crops Among Healthy Israeli Volunteers
|
N/A | |
Recruiting |
NCT06101641 -
Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals
|
N/A | |
Completed |
NCT03065283 -
Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women
|
N/A | |
Recruiting |
NCT01721811 -
Retinal Function in Relation to Transient or Chronic Challenges to Retinal Metabolism
|
N/A | |
Completed |
NCT01211717 -
The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
|
N/A | |
Completed |
NCT01568541 -
Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes
|
N/A | |
Completed |
NCT04941196 -
Bioequivalence Study of Anplag® 90mg (Ticagrelor) Tablet & Brilinta® 90 mg (Ticagrelor) Tablet in Healthy Adult Male Pakistani Subjects Under Fasting Condition
|
Phase 1 | |
Completed |
NCT05541094 -
Study of Vitamin D Fortification of Milk and Oil
|
||
Completed |
NCT05597657 -
Normal Variation of T1 Values With Cardiac Magnetic Resonance in Healthy Individuals
|
N/A | |
Completed |
NCT03728868 -
Tolerability and Risk of Adverse Events With a Probiotic Supplement
|
N/A | |
Recruiting |
NCT04513782 -
The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss
|
||
Completed |
NCT05637060 -
Bioequivalence Study of Rosuvastatin Tablet
|
N/A | |
Not yet recruiting |
NCT05110885 -
Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices
|
||
Completed |
NCT01134978 -
Neural Mechanisms of the Contextual Interference Effect: A fNIRs and EEG Study
|
Phase 1 | |
Completed |
NCT06137534 -
Upper Extremity Pattern Exercises and Respiratory Functions
|
N/A | |
Completed |
NCT04873570 -
Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistani Subjects
|
Phase 1 | |
Enrolling by invitation |
NCT01872091 -
Analysis of Neuromuscular, Circulatory and Biomechanical Responses After Cryotherapy
|
N/A | |
Completed |
NCT01872117 -
Assessment of Temperature by Infrared Thermography and Blood Conduction Velocity by Doppler After Applying Shortwave Diathermy and Microwave - Correlations With Cardiovascular and Hemodynamic Parameters
|
N/A | |
Completed |
NCT02409836 -
A Study to Assess the Ingestion of Dentifrice by Children
|
N/A |