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Headache clinical trials

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NCT ID: NCT03652714 Completed - Clinical trials for Postdural Puncture Headache

The Effect of Ganglion Sphenopalatine Block (GSP-block) Versus Placebo on Postdural Puncture Headache

Start date: September 19, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.

NCT ID: NCT03651583 Completed - Migraine Headache Clinical Trials

Examining the Efficacy of Kiko Exercises on the Prevention of Migraine Headaches

Start date: January 2006
Phase: Early Phase 1
Study type: Interventional

This pilot study hopes to show that after 3 months of Kiko training, Kiko naive patients with migraine will have a decrease in the frequency and severity of their migraines.

NCT ID: NCT03636165 Not yet recruiting - Pain, Postoperative Clinical Trials

Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Post-Craniotomy Pain in Children

Start date: September 1, 2022
Phase: Phase 4
Study type: Interventional

At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the other hand, the particularity of craniotomy adds (such as consciousness obstacle, sleepiness, et al) disturbance to the pain assessment in children. Although opioids administration is regarded as the first-line analgesic for post-craniotomy pain management, it may be associated with delayed awakening, respiratory depression, hypercarbia and it may interfere with the neurologic examination. For the avoidance of side-effects of systemic opioids, local anesthetics administered around the incision have been performed clinically. However, some studies revealed that the analgesic effect of local anesthetics was unsatisfactory due to its short pain relief duration, steroid as adjuvant can enhance postoperative analgesia and prolong postoperative analgesia time. As is reported that postoperative pain of craniotomy is mainly caused by skin incision and reflection of muscles, preventing the liberation of inflammatory mediators around the incision seems to be more effective than simply blocking nerve conduction. Thus, investigators suppose that pre-emptive scalp infiltration with steroid (Methylprednisolone) plus local anesthetic (ropivacaine) could relieve postoperative pain after craniotomy in children.

NCT ID: NCT03632928 Not yet recruiting - Migraine Disorders Clinical Trials

Day to Day Variation of Pressure Pain Threshold and Muscle Hardness

Start date: September 2018
Phase:
Study type: Observational

The aim is to establish how headache and migraine can affect muscle hardness and tenderness in migraine patients

NCT ID: NCT03626805 Completed - Migraine Disorders Clinical Trials

Muscle Tenderness and Hardness in Migraine Patients

Start date: August 13, 2017
Phase:
Study type: Observational

The aim of the study is to examine symptomatology, quantitative sensory test (QST) parameters, muscle tenderness and muscle hardness in migraine patients interictally and compare with healthy controls

NCT ID: NCT03618264 Completed - Pain, Postoperative Clinical Trials

Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Postoperative Pain After Craniotomy

Start date: April 4, 2019
Phase: Phase 4
Study type: Interventional

A majority of patients would suffer from moderate-to-severe postoperative pain after undergoing craniotomy. As a result, adequate pain control is essential for patients' prognosis and their postoperative life quality. Although opioids administration is regarded as the first-line analgesic for post-craniotomy pain management, it may be associated with delayed awakening, respiratory depression, hypercarbia and it may interfere with the neurologic examination. For the avoidance of side-effects of systemic opioids, local anesthetics administered around the incision have been performed clinically. However, some studies revealed that the analgesic effect of local anesthetics was not unsatisfactory due to its short pain relief duration. As is reported that postoperative pain of craniotomy is mainly caused by skin incision and reflection of muscles, preventing the liberation of inflammatory mediators around the incision seems to be more effective than simply blocking nerve conduction. Thus, Investigators suppose that pre-emptive scalp infiltration with steroid (dexamethasone) plus local anesthetic (ropivacaine) could relieve postoperative pain after craniotomy in adults.

NCT ID: NCT03612843 Completed - Knee Osteoarthritis Clinical Trials

Adverse Events in Dry Needling

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this prospective cohort survey study is to further explore the incidence of adverse events with dry needling by physical therapists - as well as any differences or similarities between patient-reported vs therapist-reported incidence of AEs.

NCT ID: NCT03609008 Completed - Headache Clinical Trials

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Start date: June 26, 2018
Phase: N/A
Study type: Interventional

Healthy participants vill randomly be allocated in a 2:1 order to receive 1 mg levcromakalim or placebo (isotonic saline) for 20 min. The investigator here examine the effect of levcromakalim infusion on the MMA and the MCA circumference over several hours using a high resolution MRA technique in a randomized, double-blind placebo-controlled design in healthy volunteers. The investigator hypothesized that levcromakalim induces dilatation of cranial arteries.

NCT ID: NCT03606707 Recruiting - Sleep Disturbance Clinical Trials

Efficacy of Fluoroscopic Guided Atlantoaxial Joint Injection on Head and Neck Pain and Sleep Quality in RA Patients

Start date: June 1, 2018
Phase: Early Phase 1
Study type: Interventional

Efficacy of intra-articular steroid injection for inflamed atlantoaxial joint in patients with rheumatoid arthritis Inclusion criteria Patients with rheumatoid arthritis with MRI findings of atlantoaxial joint inflammation and failure of resolution after 2 weeks systemic steroid administration Exclusion criteria Coagulopathy, allergy to contrast material, pregnancy Interventional group (AS) group, received intra-articular steroid injection for atlantoaxial joint. , in addition to methotrexate and chloroquine 400 mg per day.

NCT ID: NCT03604276 Active, not recruiting - Headache Clinical Trials

Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage

HASH4-CSF
Start date: December 1, 2017
Phase:
Study type: Observational

The purpose of this study is to determine the relationship between the Neuroinflammatory response and headache pain after subarachnoid hemorrhage.