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Headache clinical trials

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NCT ID: NCT04356963 Completed - Clinical trials for Traumatic Brain Injury

Adjunct VR Pain Management in Acute Brain Injury

Start date: September 5, 2020
Phase: N/A
Study type: Interventional

Severe and refractory pain after acute injury is a known-risk factor for chronic opioid use disorder. In this study, the investigators will use Virtual Reality (VR) immersion as a non-pharmacological adjunct to treat pain associated with acute traumatic injuries, including traumatic brain injury. The investigators hypothesize that VR therapy will decrease pain and reduce opioid use in patients with acute traumatic injuries, including TBI.

NCT ID: NCT04341298 Completed - Migraine Clinical Trials

Use of the Avulux® Lenses as an Aid in Reducing the Impact of Migraine Headaches

Start date: April 6, 2020
Phase: N/A
Study type: Interventional

The purpose of this research is to assess how well the Avulux® migraine lenses work in reducing the impact of migraine headaches as measured by improvement in an 11-point pain scale after two and four hours of device application, when compared to a control device.

NCT ID: NCT04336267 Completed - Chronic Migraine Clinical Trials

Anodal tDCS in Chronic Migraine With Medication Overuse

Start date: January 15, 2015
Phase: N/A
Study type: Interventional

Non-invasive neuromodulation has been applied in several forms of primary headaches, and its usefulness has been suggested for both episodic and chronic migraine (CM). Transcranial direct current stimulation (tDCS) represents a non-invasive electrical stimulation technique that modulates neural brain activity by means of low amplitude direct current trough surface electrodes. Very little evidence is available on the potential effect of tDCS in medication overuse and in the management of medication overuse headache (MOH), a condition frequently associated to CM. CM associated to MOH still represents a challenge for physicians and patients due to the high prevalence in the general population, the associated severe disability, and the high costs imposed by the treatment. The aim of the study was to investigate the possible application of tDCS in the management of CM associated to MOH. The primary objective of this pilot study was therefore to investigate the efficacy of anodal tDCS delivered on the primary motor cortex (M1) as add-on therapy to an in-hospital detoxification protocol in subjects affected by CM and MOH. The secondary objective was to evaluate the possible changes induced by tDCS on conventional EEG in order to obtain further clues about the effects of tDCS on brain activity.

NCT ID: NCT04331938 Completed - Headache Clinical Trials

Efficacy of Percutaneous SPG Block in Aneurysmal SAH

Start date: November 1, 2020
Phase: Phase 1
Study type: Interventional

Researchers are trying to develop alternative means to help patients with headache pain secondary to aneurysmal subarachnoid hemorrhage (bleeding about the brain).

NCT ID: NCT04327726 Completed - Clinical trials for Post-Dural Puncture Headache

Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Postdural puncture headache (PDPH) is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia. Dexmedetomidine is a highly selective, centrally acting α2-adrenergic agonist with analgesic and anxiolytic effects. Moreover, it decreases cerebral blood flow (CBF) in humans and animals secondary to cerebrovascular vasoconstriction. It has been used via the intranasal and inhalational routes for many purposes including premedication, sedation and postoperative analgesia. Because of its desirable properties, we hypothesized that dexmedetomidine nebulization could be effective in the treatment of patients suffering from PDPH after caesarean section.

NCT ID: NCT04313491 Completed - Headache Clinical Trials

Effectiveness of Yoga@Work to Reduce Head and Muscle Pain in Office Workers

Start date: February 16, 2019
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the effectiveness of a workplace yoga intervention in reducing the frequency of pain involving the head and neck area.

NCT ID: NCT04305223 Completed - Headache Clinical Trials

Dry Needling for Cervicogenic Headache

Start date: February 12, 2020
Phase: N/A
Study type: Interventional

This is a single-blinded randomized clinical trial. The primary aim of this study is to compare the effectiveness of dry needling of myofascial trigger points in the muscles of the head and cervical spine in addition to an upper extremity strengthening/stretching exercise program compared to a dry needling group alone on pain scores, cervical range of motion, pain sensitivity and changes in severity and frequency of pain symptoms in individuals with cervicogenic headache.

NCT ID: NCT04299958 Completed - Migraine Clinical Trials

Observational Prospective Study on the Presence of Typical Migraine Features in Nummular Headache Patients: The Numamig Study

Start date: April 1, 2020
Phase:
Study type: Observational [Patient Registry]

Observational analytic study with prospective cohort design that aim to describe the presence of typical features of migraine in a cohort of nummular headache patients. The aim of the study is to analyze family history, epidemiology, clinical description, presence of prodromes, postdromes and response to treatment.

NCT ID: NCT04257851 Completed - Clinical trials for Post-Dural Puncture Headache

Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache

Start date: February 15, 2020
Phase: Phase 4
Study type: Interventional

Objectives: To compare the safety and efficacy of oral theophylline versus oral sumatriptan in the treatment of post-dural puncture headache (PDPH). Background: PDPH is the most frequent complication of procedures associated with dural puncture for spinal anesthesia or following accidental dural puncture during epidural anesthesia. Since invasive treatments have known complications, pharmacologic management may be preferable. Patients and Methods: This was a prospective, randomized, double-blind, phase four clinical trial; carried out on 60 patients presented with PDPH at our hospital. Patients were randomly allocated into two equal groups (30 patients each); group T, received oral theophylline, and group S, received oral sumatriptan.

NCT ID: NCT04242290 Completed - Neck Pain Clinical Trials

Cervicospinal Posture and Pain in Cervicogenic Headache

Start date: March 20, 2019
Phase:
Study type: Observational [Patient Registry]

Cervicogenic headache (CEH) is a type of symptomatic headache that is characterized by chronic unilateral headache secondary to cervical spine dysfunction. Generally, it gets worse by neck movements, continuous placement of the head in an awkward position and exposure to external pressure on the upper cervical or occipital region. The pain was demonstrated to originate from lower cervical disc prolapse and spinal nerve roots in some studies, while it is suggested in some others to occur due to the upper cervical region as well. Although disturbed cervical alignment has been determined in tension headache and migraine, there are few studies with controversial results in the literature investigating the effects of the change in cervical lordosis on CEH. These contradictory results strongly influence the decision of whether exercise should be added to the treatment protocol in CEH and also the creation of an appropriate treatment program by the clinicians. In light of this background, the aim of this study was to compare the cervical radiographs of patients with CEH and patients with neck pain without a headache.