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Headache clinical trials

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NCT ID: NCT04950413 Completed - Headache Clinical Trials

Instrument-assisted Soft Tissue Mobilization and Phonophoresis on Trigger Points of Tension Headache

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

General purpose: It was investigate the effect of IASTM and phonophoresis on Tension Type headache. Specific Purpose: 1. It was investigate the effect of IASTM on headache frequency, PPT, pain intensity, and functional disability on trigger points of tension type headache. 2. It was investigate the effect of Lidocaine phonophoresis on headache frequency, PPT, pain intensity and functional disability on trigger points of tension type headache. 3. It was investigate the effect of IASTM and Lidocaine phonophoresis on headache frequency, PPT, pain intensity, and functional disability on trigger points of tension type headache.

NCT ID: NCT04949204 Completed - Migraine Clinical Trials

Context-awareness, Physiological Monitoring, and Machine Learning in Migraine and Cluster Headache

COPIMAC
Start date: July 1, 2020
Phase:
Study type: Observational

This is an observational, longitudinal cohort pilot study measuring physiological signals through wearable sensors combined with machine learning algorithms to detect behaviour, stress and headaches in patients with migraine and cluster headache.

NCT ID: NCT04948320 Completed - Anxiety Clinical Trials

Temporomandibular Dysfunction Affects Neck Disability, Headache, Anxiety, And Sleep Quality In Women: A Cross-Sectional Study

Start date: November 25, 2020
Phase:
Study type: Observational

The temporomandibular joint (TMJ), is the only movable joint between the joints in the head and neck system. It is a component of the chewing system and is involved in important functions such as speech, swallowing, taste and breathing. Temporomandibular dysfunction (TMD) is the general name given to various musculoskeletal problems seen in the stomatognathic system, mostly affecting the masticatory muscles and/or TMJ. TMD is the second most common musculoskeletal pain after chronic low back pain. Patients with TMD may also complain of other musculoskeletal problems, craniocervical problems, sleep problems, and anxiety disorders. The aim of this study is to investigate, compare and examine the relationship between neck dysfunction, headache and temporomandibular dysfunction severity, anxiety and sleep quality in female individuals.

NCT ID: NCT04910477 Completed - Clinical trials for Postdural Puncture Headache

Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture Headache

Start date: June 1, 2021
Phase: Phase 3
Study type: Interventional

In our study, we will compare a new route of nebulization for effectiveness between dexmedetomidine, neostigmine/atropine and saline placebo for females complained of postdural puncture headache (PDPH) after cesarean section.

NCT ID: NCT04905654 Completed - Headache, Migraine Clinical Trials

Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura

Start date: September 29, 2021
Phase: N/A
Study type: Interventional

To investigate the migraine inducing effect of levcromakalim in patients with migraine with aura.

NCT ID: NCT04892290 Completed - Clinical trials for Postdural Puncture Headache

Sphenopalatine Ganglion Block for Postdural Puncture Headache

Start date: December 1, 2019
Phase:
Study type: Observational

Background: Postdural puncture headache (PDPH), which is one of the complications of spinal anesthesia, is a condition that negatively affects the quality of life of patients, causes late mobilization and prolonged hospital stay. Sphenopalatine ganglion block (SGB) has created a minimally invasive, easy, and safe treatment alternative. Objective: Evaluating the effectiveness of topical SGB on PDPH treatment. Design: Retrospective observational study Setting: Single center tertiary level of care hospital study. The files of PDPH patients between Jan 2018 and Jan 2020 were scanned. Patients: PDPH patients aged 18-65 are included and any patients with primary/secondary headache history are excluded. Main outcome measures: Patients were divided into 2 groups. The group that given only conservative treatment was named as Group C, and the group of patients who had additionally been applied SGB was named as Group SGB. Headache severity was measured with Visual Analogue Scale (VAS) at the 1st,3rd, 12th and 24th hours of the treatment, in supine and upright position.

NCT ID: NCT04891848 Completed - Headache Disorders Clinical Trials

Assessment of Inflammation in Primary Headaches

Start date: May 1, 2018
Phase:
Study type: Observational [Patient Registry]

Headache is the most common neurological complaint accounting for % 1 to % 4 in the emergency department (ED).Every year, nearly one million people with headache attacks have been consulted by healthcare professionals at the emergency room in the United States.The International Classification of Headache Disorders (ICHD) divided headaches into two main groups: primary headaches and secondary headaches. The vast majority of cases who presented with acute headache attack in ED had a diagnosis of primary headache disorders (tension- type headache, migraine, cluster- type headache, and other primary headaches). However, secondary headache is often associated with underlying intracranial pathologies, and noted in % 10 of cases in emergency rooms. Despite the frequent presence of primary headaches, limited time setting and busy periods of medical assessment, leading diagnostic and therapeutic options due to the pathophysiological factors to be overlooked. To date, no study in the emergency care setting has explored the role of inflammation in patients with acute migraine and TTH. Investigators aimed to explore inflammatory markers [white blood cells (WBC), neutrophil, lymphocyte, platelet, neutrophil / lymphocyte ratio (NLR), and platelet / lymphocyte ratio (PLR)] in complete blood count (CBC) among MA, MO, and TTH participants who admitted to ED with acute headache attack and healthy volunteers.

NCT ID: NCT04871581 Completed - Clinical trials for Chronic Migraine, Headache

Adjunctive Treatment of Chronic Migraine Using an Oral Dental Device

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Single blinding study comparing FDA cleared device for prevention of medically diagnosed migraine pain to placebo.

NCT ID: NCT04860713 Completed - Pain Clinical Trials

An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache

Start date: April 22, 2021
Phase: Phase 4
Study type: Interventional

Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache. Most headaches managed in the ED are benign, with 90% of these headaches classified as tension, migraine, or cluster. At present, the satisfaction with ED treatment of headache is low, and despite the multitude of available medications, the evidence- based treatment options are often quite limited. There are over twenty different types of medications available to the ED clinicians for managing headache, many with different routes of administration (parenteral, intranasal, subcutaneous, and oral). Many of these medications are provided in so-called "headache cocktail", which varies based on the physician, institution, and patient preferences.

NCT ID: NCT04845451 Completed - Cluster Headache Clinical Trials

The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache

Start date: June 9, 2021
Phase:
Study type: Observational

Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated .