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Observational Study of Dental Outcomes in Head and Neck Cancer Patients — ORARAD  

Head and Neck Cancer Clinical Trial

Official title:
Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients

Clinical Trial Summary

The purpose of this study is to measure the two-year rate of tooth loss in patients who have received external beam radiation therapy with curative intent for head and neck cancer. The study will also evaluate the sequelae of radiation therapy and oral complications that may occur as a result to receiving radiation therapy.

Clinical Trial Description

This is a prospective cohort study to document dental and other oral outcomes in patients who receive external beam radiation therapy with curative intent, as part of clinical care for a head and neck cancer. Five hundred and seventy-five participants will be enrolled. All study participants will receive a baseline oral examination prior to the start of radiation therapy. Follow-up examinations and data collection will be conducted at six-month intervals up to 2 years after the start of radiation therapy. The primary outcome will be the two-year rate of tooth loss. Secondary outcomes will include measures of dental caries, periodontal health, salivary flow, and exposed bone/osteoradionecrosis. The proposed research will provide more information to inform the community about the sequelae of Radiation Therapy (RT) in head and neck cancer patients, to refine current guidelines and to design future studies on the dental management of these patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02057510
Study type Observational [Patient Registry]
Source Wake Forest University Health Sciences
Contact
Status Active, not recruiting
Phase
Start date February 2014
Completion date June 30, 2024
View Details
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