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hCG clinical trials

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NCT ID: NCT05340010 Completed - hCG Clinical Trials

Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles

Start date: January 1, 2020
Phase: Phase 4
Study type: Interventional

Successful embryo implantation is complicated process that requires synchrony between good-quality embryos and receptive endometrium. Human chorionic gonadotropin (hCG), is one of the initial embryonic signals and the major embryoendometrial relationship regulator. This study will be conducted to to investigate the role of parenteral hCG used for the transfer of cryopreserved- thawed embryos with HRT cycles in the outcome of artificially prepared frozen embryo transfer (FET) cycles.

NCT ID: NCT04744519 Completed - hCG Clinical Trials

hCG Concentration in Peripheral Maternal Blood After Embryo Transfer, Ongoing Pregnancy Rates, and Morphokinetics

Start date: January 20, 2019
Phase:
Study type: Observational

hCG is a hormone produced very early by the embryo, but not by the oocyte. It has a pivotal role in the trophoblast differentiation, and embryo implantation as well as the corpus luteum support. In spite of its well-known role, the literature about it is scarce. The aim of this retrospective study is to evaluate the relationship between the hCG concentration in peripheral maternal blood measured 11 days after embryo transfer, embryo morphokinetics pattern and the abortion and ongoing pregnancy rates. We will study patients having transference of blastocyst cultured in time lapse monitored incubators and will check all the morphokinetics parameters with the IVI database.

NCT ID: NCT04417569 Completed - Infertility Clinical Trials

A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte Maturation

Start date: February 4, 2021
Phase:
Study type: Observational

This study will determine the rise of progesterone levels after human chorionic gonadotrophin (hCG) trigger in stimulated cycles IVF/ICSI

NCT ID: NCT03495609 Completed - BRCA1 Mutation Clinical Trials

Use of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 Carriers

Start date: February 17, 2016
Phase: Phase 4
Study type: Interventional

Specific aim: To establish the proof of principle that treatment of "high breast cancer risk" women with recombinant human chorionic gonadotropin (r-hCG) will change their breast epithelium's high risk genomic profile to one similar to that identified in women with a history of early full first term pregnancy.

NCT ID: NCT02763176 Completed - hCG Clinical Trials

Measuring hCG Levels in Pregnant Women

Start date: July 2016
Phase:
Study type: Observational

This study seeks to assess trends in hCG between the 9th and 12th weeks of gestation. Women presenting at prenatal care at the study site who are 70 days gestation or less will be offered participation in the study. 75 consenting women will be asked to provide urine for an MLPT and to have blood drawn for hCG serum testing at 56-63 days, 64-70 days, and 71-77 days' gestation, and 75 consenting women will be asked to provide urine for an MLPT and to have blood drawn for hCG serum testing at 64-70 days, 71-77 days, and 78-84 days' gestation.

NCT ID: NCT02427529 Completed - HCG Clinical Trials

Muscle-Sparing Effect Of Human Chorionic Gonadotropin (hCG) During a Very Low Calorie Diet (VLCD)

Start date: May 2011
Phase: Phase 1/Phase 2
Study type: Interventional

Subjects are female patients, randomized to HCG group or placebo group, during a prospective trial, in order to determine the significance, if any, of HCG on maintaining muscle mass during a very low calorie diet in order to demonstrate the potential significance of HCG administration on preserving lean body mass while losing weight.

NCT ID: NCT01390207 Completed - hCG Clinical Trials

Earlier Triggering in Rec-FSH/GnRH Antagonist Cycles

16mm
Start date: January 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The effect of altering the timing of hCG administration on the ongoing pregnancy rate in patients stimulated with recombinant-FSH (rec-FSH)/gonadotrophin releasing hormone (GnRH) antagonists for in vitro fertilisation (IVF).