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Clinical Trial Summary

Low Dose Ruxolitinib with Calcineurin and Methotrexate vs. Calcineurin plus Methotrexate and Mycophenolate mofetil as Graft Versus Host Disease prophylaxis for HLA-haploidentical hematopoietic stem cell transplantation in low-dose antithymocyte globulin (ATG) system.


Clinical Trial Description

The is a prospective, randomized two-arm, and multicenter study. To compare the efficacy and safety of low-dose ruxolitinib combined with calcineurin and methotrexate vs. calcineurin plus methotrexate and mycophenolate mofetil as graft versus host disease prophylaxis for HLA-haploidentical hematopoietic stem cell transplantation in low-dose antithymocyte globulin (ATG) system. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04838704
Study type Interventional
Source Zhejiang University
Contact Yanmin Zhao, PhD
Phone +8615858199217
Email zjzhaoyanmin@163.com
Status Recruiting
Phase Phase 4
Start date April 8, 2021
Completion date January 31, 2025

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