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Clinical Trial Summary

A single-arm trial using Tocilizumab for acute GVHD prophylaxis after haploidentical HSCT.


Clinical Trial Description

This study will enroll haploidentical HSCT patients with high risk for acute GVHD. Tocilizumab (8mg/kg) will be added to the conventional acute GVHD prophylaxis regime (CsA+Methotrexate(MTX)+low dose mycophenolate mofetil(MMF)+ATG) on day -1 of transplant. The previous patients will be used as control. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04688021
Study type Interventional
Source First Affiliated Hospital of Zhejiang University
Contact Yi Luo, MD
Phone 86-13666609126
Email luoyijr@zju.edu.com
Status Recruiting
Phase Phase 2
Start date December 3, 2020
Completion date December 31, 2024

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