Ocular Hypertension Treatment Study (OHTS)

Glaucoma Clinical Trial

Official title:

Ocular Hypertension Treatment Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00803998
• Other study ID #: 93.01
• Status: Completed
• Phase: N/A
• First received: December 5, 2008
• Last updated: October 31, 2013
• Start date: February 1994
• Est. completion date: December 2006

Study information

• Verified date: December 2008
• Source: The New York Eye & Ear Infirmary
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The Ocular Hypertension Treatment Study is a multi-center clinical trial sponsored by the National Eye Institute, designed to determine the efficacy and safety of topically administered eye lowering medication

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: December 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

• Qualifying IOP in at least one eye of each participant must be more than or equal 24 mmHg but less than or equal to 32 mm HG calculated from two separate consecutive determination taken at least 2 hours, but not greater than 12 weeks apart.

• Normal and reliable 30-2 Humphrey Visual Fields in both eyes.

• Normal Optic disc in both eyes on clinical examinations and stereoscopic photographs as determined by the Optic Disc Reading Center.

Exclusion Criteria:

• Visual acuity worse than 20/40 in either eye on qualifying exam.

• Previous intraocular surgery: laser trabeculoplasty, laser iridotomy, filtering surgery, combined cataract extraction/filtering procedures, penetrating keratoplasty and retinal detachment repair.

Study Design

N/A

Related Conditions & MeSH terms

• Glaucoma
• Hypertension
• Ocular Hypertension

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
The New York Eye & Ear Infirmary	National Eye Institute (NEI)

References & Publications (1)

Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Kass MA. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002 Jun;120(6):714-20; discussion 829-30. — View Citation