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NCT06190119 Clinical Trial

Comparison of Aqueous Humor Adipokines in Glaucoma Patients and Healthy Controls

Glaucoma Clinical Trial

Official title:
Comparative Analysis of Aqueous Humor Adipokines in Patients With Glaucoma and Healthy Controls

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06190119
Other study ID # IRB00006761-M2023196
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 8, 2023
Est. completion date April 1, 2024

Study information
Verified date December 2023
Source Peking University
Contact Ziyao Xia, M.D.
Phone +8618810838416
Email emilyhsia@163.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to observe whether there are differences in adipokines in the aqueous humor between patients with primary open-angle glaucoma (POAG) and healthy controls

Description:

1. Inclusion criteria: Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery). 2. Exclusion criteria: 1. Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded. 2. Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery. 3. History of Ocular Trauma or Inflammation 4. Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded. 5. Pregnancy or Lactation: Females who are pregnant or lactating are excluded. 6. Presence of any retinal or optic nerve disease other than glaucoma.

Recruitment information / eligibility
Status Recruiting
Enrollment 2
Est. completion date April 1, 2024
Est. primary completion date December 31, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 85 Years
Eligibility Inclusion Criteria: - Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery). Exclusion Criteria: - Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded. - Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery. - History of Ocular Trauma or Inflammation - Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded. - Pregnancy or Lactation: Females who are pregnant or lactating are excluded. - Presence of any retinal or optic nerve disease other than glaucoma.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• none intervention
This study has no intervention

Locations
Country Name City State
China Peking University Third Hosipital Beijing Beijing

Sponsors (2)
Lead Sponsor Collaborator
Peking University Beijing Tongren Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Concentration of adipokines in aqueous humor Aqueous humor samples were assessed for adipokines and inflammatory cytokines by Luminex bead-based multiplex array Cross-sectional baseline
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