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Glaucoma clinical trials

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NCT ID: NCT04552964 Completed - Glaucoma Clinical Trials

Assessment of the Impact of an add-on and Its Smartphone Application on the Daily Management of Glaucoma

CONDORE
Start date: September 25, 2020
Phase: N/A
Study type: Interventional

Glaucoma is one of the most common chronic pathologies and affects several millions patients. Among these, many have a poorly controlled glaucoma, damaging vision and leading to blindness. One between principal reasons for poor glaucoma medication adherence is forgetfulness. To improve this issue, digital tools may benefit both ophthalmologists and patients by monitoring eye drop administration.

NCT ID: NCT04552314 Completed - Glaucoma Clinical Trials

Bleb Vascularity and the Outcomes After Trabeculectomy

Start date: July 2014
Phase:
Study type: Observational

1. Study objective: To evaluate the relationship between filtering bleb vascularity and the surgical outcomes after trabeculectomy 2. Study design: A prospective study of 51 eyes of 44 patients after primary MMC-augmented trabeculectomy. The follow-up was 12 months.

NCT ID: NCT04547036 Completed - Glaucoma Clinical Trials

Changes in Corneal Endothelial Cell Density After Transscleral ab Interno Glaucoma Gel Stent Implantation

Start date: January 30, 2020
Phase:
Study type: Observational

The objective of this study is to evaluate the change of endothelial cell count after XEN45 in patients with or without cataract operation.

NCT ID: NCT04542616 Recruiting - Glaucoma Clinical Trials

Baerveldt 350 vs Ahmed ClearPath 250 for the Treatment of Glaucoma

B350vsCP250
Start date: August 13, 2020
Phase: N/A
Study type: Interventional

To compare the safety and efficacy of Baerveldt 350 and Ahmed ClearPath 250 tube shunts in lowering IOP in glaucoma patients.

NCT ID: NCT04541524 Recruiting - Glaucoma Clinical Trials

Vienna Preserflo Cohort Study

Start date: June 5, 2020
Phase:
Study type: Observational

The Vienna Preserflo Microshunt Cohort Study is an observational study with a prospective postoperative examination in all glaucoma patients who had received a Preserflo Microshunt (PMS) as standalone procedure or in combination with cataract extraction in the time period between January and November 2019 at the Department of Ophthalmology, Medical University of Vienna. It is estimated that approximately 70 patients will be included of this cohort. The cohort will be invited for a prospective postoperative examination after 12 (±5) months of follow up. This examination shall comprise best corrected visual acuity, visual field test, intraocular pressure (IOP) measurement, slit lamp examination, fundus examination (optic disc and retina), gonioscopic assessment of PMS position, anterior segment optical coherence tomography (OCT) (shunt position, anterior chamber angle assessment, limbus shape analysis), corneal pachymetry, specular microscopy of corneal endothelial cells. Additionally, retrospective information concerning IOP, medication and visual fields of all patients will be collected from the Department of Ophthalmology as well as from the referring ophthalmologists where possible. Additionally, we will perform a comparison between two groups to compare differences in outcome measures.

NCT ID: NCT04536129 Completed - Glaucoma Clinical Trials

Effects of Topical Low Dose Preservative-free Hydrocortisone on Intraocular Pressure

Start date: November 4, 2019
Phase: N/A
Study type: Interventional

Evaluation of the safety and efficacy of hydrocortisone eye drops in the treatment of OSD (ocular surface disease) patients with and without glaucoma.

NCT ID: NCT04524416 Recruiting - Ocular Hypertension Clinical Trials

MINIject Global Long-Term Follow-up Study

STAR-GLOBAL
Start date: August 5, 2020
Phase:
Study type: Observational

The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.

NCT ID: NCT04521907 Recruiting - Clinical trials for The Incidence and Risk Factors of Glaucoma After Congenital Cataract Surgery

Correlative Study on Incidence and Risk Factors of Glaucoma-related Adverse Event at Various Durations After Congenital Cataract Surgery

Start date: May 1, 2011
Phase:
Study type: Observational

A retrospective chart review of 264 eyes from 177 patients was performed who underwent congenital cataract surgery before the age of 14 years. All patients' surgery was performed by the same experienced surgeon at the Eye Hospital of Wenzhou Medical University from May 2011 to March 2019. We recorded patient demographics and incidence and risk factors for glaucoma-related adverse event. This study to identify the incidence of and risk factors associated with postoperative glaucoma at various durations after congenital cataract surgery.

NCT ID: NCT04519619 Recruiting - Clinical trials for Neovascular Glaucoma

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Start date: November 27, 2020
Phase:
Study type: Observational

This is a prospective, observational, multi-center and post-authorization safety study that includes patients with a diagnosis of Neovascular Glaucoma. The investigator will have made the decision to use Eylea for treatment. The objective of this study is to assess safety and effectiveness of Eylea using in real clinical practice. Patients will be followed for a time period of 6 months from start of Eylea treatment or until it is no longer possible (e.g. lost to follow-up). In total, 480 patients will be recruited. For each patient, data are collected as defined in the electronic case report form (eCRF) at the initial visit, follow-up visit and final visit, either by routine clinical visits (as per investigators routine practice).

NCT ID: NCT04517786 Active, not recruiting - Clinical trials for Glaucoma, Open-Angle Glaucoma Eye

MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

The study will assess safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.