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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT04994457 Enrolling by invitation - Glaucoma Clinical Trials

Patient Performance on Virtual Reality Visual Field Devices as Compared to Standard of Care

Start date: October 30, 2021
Phase:
Study type: Observational

The purpose of this research is to study the effectiveness and patient experience when measuring visual fields using virtual reality goggles.

NCT ID: NCT04722861 Enrolling by invitation - Glaucoma Suspect Clinical Trials

Development of the Glaucoma Visual Functioning Questionnaire-40 and Its Psychometric Properties

Start date: September 8, 2020
Phase:
Study type: Observational

The objective of this study is to develop and test the psychometric properties of a self-report questionaire, the Glaucoma Visual Functioning Questionnaire-40 (GVFQ-40), which was designed to measure the difficulty of daily activities of glaucoma patients and evaluate the effectiveness of clinical treatment or rehabilitation interventions.

NCT ID: NCT04590651 Enrolling by invitation - Cataract Clinical Trials

Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma

PHACOPXG
Start date: September 11, 2020
Phase: N/A
Study type: Interventional

The study aims to document the effect cataract surgery has on the pseudoexfoliation and pseudoexfoliation glaucoma eye. Details such has patient history, history of possible glaucoma, intraocular pressure, status of the eye, operation parameters and postoperative effect will be documented. The study is prospective and randomised . Patients will be divided in to two groups: in one standard phacoemulsification cataract surgery will be preformed. In the second group the anterior chamber angel will be aspirated an extra minute at the end of the case with the IA probe. The aim is to determine weather this extra aspiration will have an effect on postoperative intraocular pressure and other parameters.

NCT ID: NCT04381611 Enrolling by invitation - Surgery Clinical Trials

INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register

Start date: January 15, 2019
Phase:
Study type: Observational [Patient Registry]

The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in nature.Patients' medical data contained in the register will be analysed to determine the efficacy of the treatments they received during their follow-up at the investigation centre.

NCT ID: NCT04342052 Enrolling by invitation - Glaucoma Clinical Trials

Glaucoma After Congenital Cataract Surgery

Start date: January 1, 2011
Phase:
Study type: Observational

To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.

NCT ID: NCT04323930 Enrolling by invitation - Primary Glaucoma Clinical Trials

eyeWatch vs. Trabeculectomy RCT (evT)

evT
Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The confirm the performance and safety of the eyeWatch System as first-line filtering surgery and compare its outcomes to trabeculectomy

NCT ID: NCT04010994 Enrolling by invitation - Glaucoma Clinical Trials

Treatment of Patients With Optic Nerve Damage Patients Using Electrostimulation

HomeStim
Start date: August 5, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the present study is to investigate the possibilities of visual field enhancement with electrical stimulation (ES) as a home stimulation method, in a total of 50 patients with optical neuropathy, who have already been treated with ES in the past. Furthermore, factors responsible for response variability and treatment effectiveness are also explored: (i) the role of mental stress (or stress resilience), (ii) the status of biomarkers, such as the systemic stress hormone levels and blood supply to the eye and brain (specifically vascular dysregulation) and (iii) the influence of personality, anxiety, depression and lifestyle. The study serves to further validate this ES procedure for the treatment of visual impairment. Specifically, better efficacy, better compliance, lowest response variability are expected after long-term home use.

NCT ID: NCT03891446 Enrolling by invitation - Ocular Hypertension Clinical Trials

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

Maia
Start date: March 27, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate the long-term safety and efficacy of Bimatoprost Sustained Release (SR) in patients with open-angle glaucoma or ocular hypertension who completed 1 of the 4 Phase 3 Bimatoprost SR studies (192024-091, -092, -093, or -095) and received Bimatoprost SR or who received commercial DURYSTA (Bimatoprost SR) in the open-label Phase 4 ARGOS study (MED-MA-EYE-0648) and completed (or exited early from) the study.

NCT ID: NCT03760055 Enrolling by invitation - Glaucoma Clinical Trials

Assessment of Visual Function With a Portable Brain-computer Interface

Start date: February 11, 2019
Phase:
Study type: Observational

1. The purpose of this study is to evaluate the nGoggle's accuracy and repeatability in detecting visual function loss. In addition, the ability to stage glaucomatous damage and investigate the relationship between nGoggle metrics and neural damage in glaucoma will also be evaluated. 2. Longitudinal study, including 200 patients with: glaucoma, suspected of having glaucoma, nonglaucomatous optic neuropathies, AMD, retinal degenerations, other diseases involving the visual pathways, besides healthy controls. Subjects will perform standard ophthalmological exams, and the following research tests: electroencephalogram, visual evoked potentials, and questionnaires. 3. Statistical analyses will be performed by the PI using the software Stata, MATLAB, and MPLUS. Risks are low, consisting of some discomfort, fatigue, dizziness or motion sickness.

NCT ID: NCT03590249 Enrolling by invitation - Glaucoma Clinical Trials

Effects of a Single Osteopathic Manipulative Treatment (OMT) on Intraocular Pressure (IOP) Reduction

OMT/IOP
Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Glaucoma is a group of eye diseases, which in most cases produce increased pressure within the eye (intraocular pressure or IOP). Over time, the elevated IOP causes damage to the optic nerve, which can then lead to visual loss and if unchecked, to complete blindness over the course of years. OMT has been shown to affect cranial structure physiology including the possibility of lowering IOP by improving the drainage of intraocular fluid. This randomized study is designed to obtain data to evaluate the effect of OMT on IOP lowering and, if supportive, provide preliminary data for larger clinical trials.